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采用 All-on-4 即刻负重策略的种植体存活率和边缘骨丧失:一项 1 至 4 年随访的临床回顾性研究。

Implant survival rate and marginal bone loss with the all-on-4 immediate-loading strategy: A clinical retrospective study with 1 to 4 years of follow-up.

机构信息

Graduate student, Graduate Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang, PR China.

Deputy chief dentist, Department of Endodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang, PR China.

出版信息

J Prosthet Dent. 2023 Dec;130(6):849-857. doi: 10.1016/j.prosdent.2021.12.020. Epub 2022 Feb 12.

Abstract

STATEMENT OF PROBLEM

Assessing peri-implant marginal bone loss (MBL) and its risk factors with cone beam computed tomography (CBCT) may clarify the risk factors for the all-on-4 (5 or 6) strategy and further improve its survival rate.

PURPOSE

The purpose of this retrospective clinical study was to evaluate the implant survival rate, MBL, and associated risk factors of all-on-4 (5 or 6) prostheses after 1 to 4 years of follow-up with CBCT.

MATERIAL AND METHODS

A total of 56 participants rehabilitated with 325 implants by using the all-on-4 (5 or 6) concept between October 2015 and December 2019 were included. Outcome measures were cumulative implant survival (life-table analysis) and MBL. Four CBCT scans, a scan immediately after surgery (T0), a scan 1 year after surgery (T1), a scan 2 years after surgery (T2), and a scan 3 to 4 years after treatment (T3), were obtained to evaluate the MBL. The Pearson correlation coefficient analysis and linear mixed models were performed to assess the potential risk factors for MBL (α=.05).

RESULTS

The implant survival rate was 99.38%, and the prosthesis survival rate was 100%. The reductions in the vertical buccal bone height (△VBBH) were 0.74 ±0.10 mm (T0-T1), 0.37 ±0.12 mm (T1-T2), and 0.15 ±0.14 mm (T2-T3). Except for T2-T3, the △VBBH showed a significant difference at T0-T1 and T1-T2 (P≤.05). The alterations in vertical mesial bone height (VMBH), vertical distal bone height (VDBH), and vertical lingual bone height (VLBH) were similar to the trend observed in VBBH. The △VBBH (T0-T3) was negatively correlated with the horizontal buccal bone thickness (HBBT) (T0) (r=-.394, P<.001). Linear mixed models revealed that factors such as smoking (P=.001), mandible implant site (P<.001), immediate implant (P=.026), tilted implant (P<.001), female sex (P=.003), systemic disease (P=.025), and bruxism (P=.022) negatively affected MBL. The cantilever length (CL) also had a negative effect on MBL around the implants at the distal extension (P<.001).

CONCLUSIONS

The high implant and prosthesis survival rates and low MBL confirmed the predictability of the all-on-4 (5 or 6) concept. Smoking, mandible implant site, systemic disease, bruxism, female sex, immediate implant, tilted implant, and CL were identified as potential risk factors for MBL.

摘要

问题陈述

使用锥形束计算机断层扫描 (CBCT) 评估种植体周围边缘骨损失 (MBL) 及其危险因素,可以阐明全口种植体即刻负重 (5 或 6 颗种植体) 策略的危险因素,并进一步提高其存活率。

目的

本回顾性临床研究的目的是使用 CBCT 评估全口种植体即刻负重 (5 或 6 颗种植体) 后 1 至 4 年的种植体存活率、MBL 及其相关危险因素。

材料和方法

共纳入 2015 年 10 月至 2019 年 12 月期间使用全口种植体即刻负重 (5 或 6 颗种植体) 概念修复的 56 名患者,共植入 325 颗种植体。主要结局指标为累积种植体存活率 (寿命表分析) 和 MBL。获得了 4 次 CBCT 扫描,分别为手术即刻 (T0)、术后 1 年 (T1)、术后 2 年 (T2) 和治疗后 3 至 4 年 (T3) 的扫描,以评估 MBL。采用 Pearson 相关系数分析和线性混合模型评估 MBL 的潜在危险因素 (α=.05)。

结果

种植体存活率为 99.38%,修复体存活率为 100%。颊侧骨高度的垂直减少量 (△VBBH) 分别为 0.74 ±0.10 mm(T0-T1)、0.37 ±0.12 mm(T1-T2)和 0.15 ±0.14 mm(T2-T3)。除 T2-T3 外,T0-T1 和 T1-T2 时 △VBBH 差异有统计学意义 (P≤.05)。近中骨高度 (VMBH)、远中骨高度 (VDBH) 和舌侧骨高度 (VLBH) 的变化趋势与 VBBH 相似。△VBBH (T0-T3) 与颊侧骨水平厚度 (HBBT) (T0) 呈负相关 (r=-.394,P<.001)。线性混合模型显示,吸烟 (P=.001)、下颌种植体部位 (P<.001)、即刻种植体 (P=.026)、倾斜种植体 (P<.001)、女性 (P=.003)、全身性疾病 (P=.025) 和磨牙症 (P=.022) 等因素对 MBL 有负面影响。悬臂长度 (CL) 也对种植体在远中延伸部位的 MBL 有负面影响 (P<.001)。

结论

高的种植体和修复体存活率以及低的 MBL 证实了全口种植体即刻负重 (5 或 6 颗种植体) 概念的可预测性。吸烟、下颌种植体部位、全身性疾病、磨牙症、女性、即刻种植体、倾斜种植体和 CL 被确定为 MBL 的潜在危险因素。

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