Haig G
Int J Tissue React. 1986;8(2):145-7.
A double-blind, parallel trial was undertaken with 3% benzydamine cream compared with a matching placebo, on patients suffering acute soft-tissue injuries. 21 patients received active material and 22 received placebo material. Patients applied the cream lightly 6 times a day for 6 days. Assessments were made (by the same physician) on days 0, 2, 4 and 6, and signs and symptoms were graded as "absent", "slight", "moderate" or "severe". Thermograms were taken on day 0 and day 6. The results showed significant relief of spontaneous pain, significant reduction in tenderness on pressure and in swelling on days 2, 4 and 6 of the trial, and a significant reduction in functional impairment on days 4 and 6, in the patients who had received the 3% benzydamine cream.
对患有急性软组织损伤的患者进行了一项双盲平行试验，将3% 苄达明乳膏与匹配的安慰剂进行比较。21名患者接受活性药物，22名患者接受安慰剂。患者每天轻轻涂抹乳膏6次，持续6天。在第0、2、4和6天（由同一位医生）进行评估，体征和症状分为“无”、“轻微”、“中度”或“重度”。在第0天和第6天进行热成像检查。结果显示，接受3%苄达明乳膏治疗的患者在试验的第2、4和6天，自发疼痛明显缓解，压痛和肿胀明显减轻，在第4和6天功能障碍明显减轻。
