Clark Jessica, Stolk Wilma A, Basáñez María-Gloria, Coffeng Luc E, Cucunubá Zulma M, Dixon Matthew A, Dyson Louise, Hampson Katie, Marks Michael, Medley Graham F, Pollington Timothy M, Prada Joaquin M, Rock Kat S, Salje Henrik, Toor Jaspreet, Hollingsworth T Déirdre
Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Old Road Campus, Headington, Oxford, OX3 7LF, UK.
Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.
Gates Open Res. 2022 Feb 2;5:112. doi: 10.12688/gatesopenres.13327.2. eCollection 2021.
The World Health Organization recently launched its 2021-2030 roadmap, an updated call to arms to end the suffering caused by neglected tropical diseases. Modelling and quantitative analyses played a significant role in forming these latest goals. In this collection, we discuss the insights, the resulting recommendations and identified challenges of public health modelling for 13 of the target diseases: Chagas disease, dengue, human African trypanosomiasis (gHAT), lymphatic filariasis (LF), onchocerciasis, rabies, scabies, schistosomiasis, soil-transmitted helminthiases (STH), taeniasis/ cysticercosis, trachoma, visceral leishmaniasis (VL) and yaws. This piece reflects the three cross-cutting themes identified across the collection, regarding the contribution that modelling can make to timelines, programme design, drug development and clinical trials.
世界卫生组织最近发布了其2021-2030年路线图，这是一份更新的战斗号召，旨在终结被忽视热带病所带来的痛苦。建模和定量分析在制定这些最新目标中发挥了重要作用。在本论文集中，我们讨论了针对13种目标疾病开展公共卫生建模的见解、由此得出的建议以及所发现的挑战，这些疾病包括：恰加斯病、登革热、非洲人类锥虫病（gHAT）、淋巴丝虫病（LF）、盘尾丝虫病、狂犬病、疥疮、血吸虫病、土壤传播的蠕虫病（STH）、绦虫病/囊尾蚴病、沙眼、内脏利什曼病（VL）和雅司病。本文反映了整个论文集中确定的三个贯穿各领域的主题，即建模对时间表、项目设计、药物开发和临床试验的贡献。
