Settaf A, Gugenheim J, Houssin D, Bismuth H
J Chir (Paris). 1986 Feb;123(2):141-4.
A technique for orthotopic hepatic transplantation in the rat uses polyethylene cuffs to re-establish vascular and biliary continuity. Introduction of the suprahepatic cuff into the intrahepatic vena cava of the receiver rat, after partial hepatectomy, reduces the duration of vascular clamping and improves survival of grafted rats (long-term survival: 70%). This technique is simple to reproduce after several weeks of training and can allow research teams to study immunologic mechanisms of tolerance or rejection of liver allografts in the pure strain rat.
一种用于大鼠原位肝移植的技术采用聚乙烯套管来重建血管和胆管的连续性。在受体大鼠部分肝切除后，将肝上套管置入受体大鼠的肝内静脉，可缩短血管钳夹时间并提高移植大鼠的存活率（长期存活率：70%）。经过几周的训练后，该技术很容易重复操作，并且能让研究团队在纯系大鼠中研究肝同种异体移植物耐受或排斥的免疫机制。
