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呼吸道合胞病毒（RSV）感染的发病率：德国科隆 0-4 岁儿童中 RSV 与严重急性呼吸综合征冠状病毒 2 感染的比较。

Morbidity of Respiratory Syncytial Virus (RSV) Infections: RSV Compared With Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Children Aged 0-4 Years in Cologne, Germany.

机构信息

University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatrics, Cologne, Germany.

University of Cologne, Faculty of Medicine and University Hospital Cologne, Institute of Virology, Cologne, Germany.

出版信息

J Infect Dis. 2022 Dec 13;226(12):2050-2053. doi: 10.1093/infdis/jiac052.

DOI:10.1093/infdis/jiac052

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8903412/

Abstract

The aim of this retrospective analysis was to provide information on how infections with respiratory syncytial virus (RSV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) differ in symptoms, clinical course, outcome, and utilization of hospital care. We investigated 748 polymerase chain reaction results from symptomatic children aged 0-4 years in Cologne, Germany. One hundred sixty-nine patients tested positive for RSV (22.6%) and 24 children for SARS-CoV-2 (3.2%). Symptomatic patients with RSV infection were hospitalized significantly longer. RSV-positive patients needed oxygen supplementation significantly more often as well as high-flow therapy. With regard to care efforts, RSV-infected patients put higher pressure on the hospital and utilized more hospital resources.

摘要

本回顾性分析旨在提供有关呼吸道合胞病毒 (RSV) 和严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 感染在症状、临床过程、结局和医院护理利用方面的差异信息。我们调查了德国科隆 748 名有症状的 0-4 岁儿童的聚合酶链反应结果。169 名患者 RSV 检测呈阳性（22.6%），24 名儿童 SARS-CoV-2 检测呈阳性（3.2%）。患有 RSV 感染的有症状患者住院时间明显更长。需要补充氧气的 RSV 阳性患者以及需要高流量治疗的患者明显更多。在护理方面，感染 RSV 的患者对医院的压力更大，利用了更多的医院资源。