Derkenne Clément, Jost Daniel, Roquet Florian, Corpet Pascal, Frattini Benoit, Kedzierewicz Romain, Bellec Guillaume, Rajon Benjamin, Fernandez Marianne, Loeb Thomas, Pierantoni Emmanuel, Lamblin Antoine, Prunet Bertrand
Paris Fire Brigade, Paris, France
Paris Fire Brigade, Paris, France.
Emerg Med J. 2022 May;39(5):347-352. doi: 10.1136/emermed-2021-211417. Epub 2022 Feb 16.
Emergency physicians can use a manual or an automated defibrillator to provide defibrillation of patients who had out-of-hospital cardiac arrest (OHCA). Performance of emergency physicians in identifying shockable rhythm with a manual defibrillator has been poorly explored whereas that of automated defibrillators is well known (sensitivity 0.91-1.00, specificity 0.96-0.99). We conducted this study to estimate the sensitivity/specificity and speed of shock/no-shock decision-making by prehospital emergency physicians for shockable or non-shockable rhythm, and their preference for manual versus automated defibrillation.
We developed a web application that simulates a manual defibrillator (https://simul-shock.firebaseapp.com/). In 2019, all (262) emergency physicians of six French emergency medical services were invited to participate in a study in which 60 ECG rhythms from real OHCA recordings were successively presented to the physicians for determination of whether they would or would not administer a shock. Time to decision was recorded. Answers were compared with a gold standard (concordant answers of three experts). We report sensitivity for shockable rhythms (decision to shock) and specificity for non-shockable rhythms (decision not to shock). Physicians were also asked whether they preferred manual or automated defibrillation.
Among 215 respondents, we were able to analyse results for 190 physicians. 57% of emergency physicians preferred manual defibrillation. Median (IQR) sensitivity for a shock delivery for shockable rhythm was 0.91 (0.81-1.00); median specificity for no-shock delivery for non-shockable rhythms was 0.91 (0.80-0.96). More precisely, sensitivities for shock delivery for ventricular tachycardia (VT) and coarse ventricular fibrillation (VF) were both 1.0 (1.0-1.0); sensitivity for fine VF was 0.6 (0.2-1). Specificity for not shocking a pulseless electrical activity (PEA) was 0.83 (0.72-0.86), and for asystole, specificity was 0.93 (0.86-1). Median speed of decision-making (in seconds) were: VT 2.0 (1.6-2.7), coarse VF 2.1 (1.7-2.9), asystole 2.4 (1.8-3.5), PEA 2.8 (2.0-4.2) and fine VF 2.8 (2.1-4.3).
Global sensitivity and specificity were comparable with published automated external defibrillator studies. Shockable rhythms with the best clinical prognoses (VT and coarse VF) were very rapidly recognised with very good sensitivity. The decision-making for fine VF or asystole and PEA was less accurate.
急诊医生可使用手动或自动除颤器为院外心脏骤停(OHCA)患者进行除颤。急诊医生使用手动除颤器识别可除颤心律的表现鲜有研究,而自动除颤器的表现则广为人知(敏感性0.91 - 1.00,特异性0.96 - 0.99)。我们开展本研究以评估院前急诊医生对可除颤或不可除颤心律进行除颤/不除颤决策的敏感性/特异性及速度,以及他们对手动与自动除颤的偏好。
在215名受访者中,我们能够分析190名医生的结果。57%的急诊医生更喜欢手动除颤。可除颤心律进行电击的中位(四分位间距)敏感性为0.91(0.81 - 1.00);不可除颤心律不进行电击的中位特异性为0.91(0.80 - 0.96)。更确切地说,室性心动过速(VT)和粗颤型室颤(VF)进行电击的敏感性均为1.0(1.0 - 1.0);细颤型VF的敏感性为0.6(0.2 - 1)。无脉电活动(PEA)不进行电击的特异性为0.83(0.72 - 0.86),心脏停搏时特异性为0.93(0.86 - 1)。决策的中位速度(以秒计)为:VT 2.0(1.6 - 2.7),粗颤型VF 2.1(1.7 - 2.9),心脏停搏2.4(1.8 - 3.5),PEA 2.8(2.0 - 4.2)和细颤型VF 2.8(2.1 - 4.3)。
总体敏感性和特异性与已发表的自动体外除颤器研究相当。具有最佳临床预后的可除颤心律(VT和粗颤型VF)能被非常快速地识别,敏感性很高。对细颤型VF或心脏停搏及PEA的决策准确性较低。