Tsujino Kohei, Takai Satoshi, Kanemitsu Takuya, Tsuji Yuichiro, Yagi Ryokichi, Hiramatsu Ryo, Kameda Masahiro, Ikeda Naokado, Nonoguchi Naosuke, Furuse Motomasa, Kawabata Shinji, Takami Toshihiro, Wanibuchi Masahiko
Department of Neurosurgery, Osaka Medical and Pharmaceutical University.
Neurol Med Chir (Tokyo). 2022 Apr 15;62(4):209-213. doi: 10.2176/jns-nmc.2021-0321. Epub 2022 Feb 16.
Spinal intramedullary metastasis is an extremely rare event that occurs in advanced cancer. The surgical indications for spinal intramedullary metastasis are highly limited because of surgical difficulty and poor prognosis. In this technical case report, we present a rare case of spinal intramedullary metastasis from the lung that recurred late after local radiation to the spinal cord. The patient progressively experienced relapsed buttock pain and developed gait and urination disorders late after treatment for lung cancer. Imaging examinations suggested the recurrence of spinal intramedullary metastasis in the conus medullaris. Systemic examinations revealed no apparent recurrence in other organs, including the primary lung lesions. Gross total resection of the tumor within the conus medullaris was safely performed using the unilateral posterolateral (PLS) approach and by addition of the contralateral PLS approach. To the best of our knowledge, this is the first case in which a spinal intramedullary metastatic tumor was successfully removed using a bilateral PLS approach.
脊髓髓内转移是晚期癌症中极为罕见的事件。由于手术难度大且预后差,脊髓髓内转移的手术指征非常有限。在本技术病例报告中,我们呈现了一例罕见的肺源性脊髓髓内转移病例,该病例在脊髓局部放疗后晚期复发。患者在肺癌治疗后逐渐出现复发性臀部疼痛,并在晚期出现步态和排尿障碍。影像学检查提示圆锥部脊髓髓内转移复发。全身检查未发现其他器官有明显复发,包括原发性肺部病变。采用单侧后外侧(PLS)入路并加用对侧PLS入路,安全地对圆锥部肿瘤进行了全切除。据我们所知,这是首例采用双侧PLS入路成功切除脊髓髓内转移瘤的病例。