Takami Toshihiro, Yamagata Toru, Ohata Kenji
Department of Neurosurgery, Osaka City University Graduate School of Medicine.
Neurol Med Chir (Tokyo). 2013;53(12):920-7. doi: 10.2176/nmc.tn2012-0419. Epub 2013 Oct 29.
Posterolateral sulcus (PLS) approach of the spinal cord, being equivalent to the dorsal root entry zone myelotomy, may offer the satisfactory exposure of the spinal intramedullary tumor if applied appropriately. Eight consecutive patients with spinal intramedullary tumors of lateral location underwent the surgery of PLS approach in our institute. There were 6 male and 2 female patients, ranging in age from 34 to 72 years (mean, 57 years). PLS approach was indicated for the intramedullary tumor situated laterally in the spinal cord and that do not contact the posterior or lateral surfaces on magnetic resonance (MR) images before surgery. Total removal of the tumor was achieved in 6 cases except of 2 cases of anaplastic astrocytoma. All 6 patients with total removal of the tumor demonstrated the modest or mild deterioration of motor function on the approach side early after surgery, which resolved within 1 month after surgery. Average grade of the modified McCormick functional schema was 3.5 before surgery and improved to 3.0 at 3 months after surgery. These 6 patients demonstrated satisfactory pain relief early after surgery. Average grade of the sensory pain scale was 2.7 before surgery and improved to 1.7 at 3 months after surgery. PLS approach can be one of the surgical choices to the spinal intramedullary tumors, if applied appropriately. Better indication for PLS approach may be the tumors of the uneven location within the spinal cord associated with moderate or severe local pain.
脊髓后外侧沟(PLS)入路等同于背根入髓区脊髓切开术,若应用得当,可为脊髓髓内肿瘤提供满意的显露。我院对8例连续的脊髓髓外侧面肿瘤患者采用PLS入路进行手术。患者中男性6例,女性2例,年龄34至72岁(平均57岁)。PLS入路适用于术前磁共振(MR)图像显示位于脊髓外侧且未接触后表面或外侧表面的髓内肿瘤。除2例间变性星形细胞瘤外,6例患者肿瘤实现全切除。6例肿瘤全切除患者术后早期均出现入路侧运动功能轻度或中度恶化,术后1个月内恢复。术前改良 McCormick 功能分级平均为3.5级,术后3个月改善至3.0级。这6例患者术后早期疼痛缓解满意。术前感觉疼痛评分平均为2.7分,术后3个月改善至1.7分。若应用得当,PLS入路可作为脊髓髓内肿瘤的手术选择之一。PLS入路更好的适应证可能是脊髓内位置不均且伴有中度或重度局部疼痛的肿瘤。