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Attack of the Clones: Microglia in Health and Disease.

作者信息

Manjally Amritha Vinayak, Tay Tuan Leng

机构信息

Faculty of Biology, University of Freiburg, Freiburg, Germany.

BrainLinks-BrainTools Centre, University of Freiburg, Freiburg, Germany.

出版信息

Front Cell Neurosci. 2022 Jan 31;16:831747. doi: 10.3389/fncel.2022.831747. eCollection 2022.

DOI:10.3389/fncel.2022.831747
PMID:35173585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8841846/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9700/8841846/8231bb450b8a/fncel-16-831747-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9700/8841846/8231bb450b8a/fncel-16-831747-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9700/8841846/8231bb450b8a/fncel-16-831747-g0001.jpg

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本文引用的文献

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TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.TREM2 与 TDP-43 相互作用,介导小胶质细胞对 TDP-43 相关神经退行性变的神经保护作用。
Nat Neurosci. 2022 Jan;25(1):26-38. doi: 10.1038/s41593-021-00975-6. Epub 2021 Dec 16.
2
Microglia contribute to the propagation of Aβ into unaffected brain tissue.小胶质细胞有助于 Aβ 向未受影响的脑组织扩散。
Nat Neurosci. 2022 Jan;25(1):20-25. doi: 10.1038/s41593-021-00951-0. Epub 2021 Nov 22.
3
Glial Purinergic Signaling in Neurodegeneration.
Res Sq. 2024 Sep 27:rs.3.rs-4986866. doi: 10.21203/rs.3.rs-4986866/v1.
4
Defective phagocytosis leads to neurodegeneration through systemic increased innate immune signaling.吞噬作用缺陷通过全身性先天免疫信号增强导致神经退行性变。
iScience. 2023 Sep 26;26(10):108052. doi: 10.1016/j.isci.2023.108052. eCollection 2023 Oct 20.
5
Late-Stage Glioma Is Associated with Deleterious Alteration of Gut Bacterial Metabolites in Mice.晚期胶质瘤与小鼠肠道细菌代谢物的有害改变有关。
Metabolites. 2022 Mar 25;12(4):290. doi: 10.3390/metabo12040290.
神经退行性变中的胶质细胞嘌呤能信号传导。
Front Neurol. 2021 May 14;12:654850. doi: 10.3389/fneur.2021.654850. eCollection 2021.
4
Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain.营养不良的小胶质细胞与神经退行性疾病有关,而与人类大脑的健康衰老无关。
Neurobiol Aging. 2021 Mar;99:19-27. doi: 10.1016/j.neurobiolaging.2020.12.003. Epub 2021 Jan 7.
5
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