Li Wei, Xu Jiacheng, Li Tao, Bi Yuhe, Ren Weicai, Wei Shengchao
Department of Anorectal Surgery, Jinan City People's Hospital Jinan 271199, Shangdong, China.
Am J Transl Res. 2022 Jan 15;14(1):432-439. eCollection 2022.
To explore the efficacy of posterior median anal incision plus incision and drainage of anal sinus on chronic anal fissure (CAF), and its influence on incidence and recurrence of postoperative infection.
Altogether 130 patients with CAF treated during January 2017 and January 2021 were included and divided into a research group (RG) and control group (CG). Among them, 80 patients in the RG were treated with posterior median anal incision and expansion plus anal sinus incision and drainage, while 50 in the CG were treated with lateral internal sphincterotomy. Clinical indexes (wound healing time, recovery time of bowel sounds, intraoperative blood loss, length of stay), levels of inflammatory factors (IL-6, IL-8, CRP) before and one week after treatment, changes of psychological and emotional scores (SAS, SDS scores) before and 6 months after treatment, sleep and scores of daily activities after admission and 6 months after treatment, VAS scores at 1 day, 1 week and 2 weeks after operation, compliance, total effective rate, and incidence and recurrence rate of postoperative incision infection were compared between the groups.
Compared with the CG, the wound healing time, recovery time of bowel sounds and length of stay were shorter, and intraoperative blood loss was lower in the RG; the levels of IL-6, IL-8 and CRP were lower in RG one week after treatment. Six months after treatment, the SAS, SDS and PSQI scores were lower, the ADL scores were higher, the compliance and total effective rate were higher, and the incidence and recurrence rate of postoperative incision infection were lower in the RG.
Posterior median anal incision plus incision drainage of the anal sinus has better efficacy on CAF, and can effectively reduce the incidence of postoperative infection and recurrence.
探讨肛门后正中切口联合肛窦切开引流术治疗慢性肛裂(CAF)的疗效及其对术后感染发生率和复发率的影响。
纳入2017年1月至2021年1月期间治疗的130例CAF患者,分为研究组(RG)和对照组(CG)。其中,RG组80例患者采用肛门后正中切口扩创联合肛窦切开引流术治疗,CG组50例患者采用侧方内括约肌切开术治疗。比较两组患者的临床指标(伤口愈合时间、肠鸣音恢复时间、术中出血量、住院时间)、治疗前及治疗后1周炎症因子(IL-6、IL-8、CRP)水平、治疗前及治疗后6个月心理情绪评分(SAS、SDS评分)、入院时及治疗后6个月睡眠及日常活动评分、术后1天、1周及2周VAS评分、依从性、总有效率以及术后切口感染发生率和复发率。
与CG组相比,RG组伤口愈合时间、肠鸣音恢复时间和住院时间更短,术中出血量更少;治疗后1周RG组IL-6、IL-8和CRP水平更低。治疗后6个月,RG组SAS、SDS和PSQI评分更低,ADL评分更高,依从性和总有效率更高,术后切口感染发生率和复发率更低。
肛门后正中切口联合肛窦切开引流术治疗CAF疗效更佳,能有效降低术后感染发生率和复发率。