• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Editorial: Induced Pluripotent Stem Cell-Based Disease Modeling and Drug Discovery: Can We Recapitulate Cardiovascular Disease on a Culture Dish?

作者信息

Yuasa Shinsuke, Yazawa Masayuki, Lee Jong-Kook

机构信息

Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.

Department of Rehabilitation and Regenerative Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, United States.

出版信息

Front Cell Dev Biol. 2022 Jan 31;9:831304. doi: 10.3389/fcell.2021.831304. eCollection 2021.

DOI:10.3389/fcell.2021.831304
PMID:35174176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8841961/
Abstract
摘要

相似文献

1
Editorial: Induced Pluripotent Stem Cell-Based Disease Modeling and Drug Discovery: Can We Recapitulate Cardiovascular Disease on a Culture Dish?社论：基于诱导多能干细胞的疾病建模与药物发现：我们能否在培养皿上重现心血管疾病？
Front Cell Dev Biol. 2022 Jan 31;9:831304. doi: 10.3389/fcell.2021.831304. eCollection 2021.
2
Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discovery.用于心血管疾病的诱导多能干细胞：从以产品为重点的疾病建模到以过程为重点的疾病发现。
Regen Med. 2015;10(6):773-83. doi: 10.2217/rme.15.41. Epub 2015 Oct 6.
3
[Constructing iPS cell-based platforms for disease modeling and drug discovery in cardiovascular fields: Phenotype analysis using self-organization and new imaging techniques].[构建用于心血管疾病建模和药物发现的基于诱导多能干细胞的平台：利用自组织和新成像技术进行表型分析]
Nihon Yakurigaku Zasshi. 2020;155(5):300-302. doi: 10.1254/fpj.20043.
4
Human Induced Pluripotent Stem-Cardiac-Endothelial-Tumor-on-a-Chip to Assess Anticancer Efficacy and Cardiotoxicity.人诱导多能干细胞-心脏内皮肿瘤芯片用于评估抗癌疗效和心脏毒性。
Tissue Eng Part C Methods. 2020 Jan;26(1):44-55. doi: 10.1089/ten.TEC.2019.0248. Epub 2020 Jan 3.
5
Induced pluripotent stem cells as a new strategy for cardiac regeneration and disease modeling.诱导多能干细胞作为心脏再生和疾病建模的新策略。
J Mol Cell Cardiol. 2013 Sep;62:43-50. doi: 10.1016/j.yjmcc.2013.04.022. Epub 2013 Apr 30.
6
Human Induced Pluripotent Stem Cell-Derived Endothelial Cells for Three-Dimensional Microphysiological Systems.用于三维微生理系统的人诱导多能干细胞衍生的内皮细胞
Tissue Eng Part C Methods. 2017 Aug;23(8):474-484. doi: 10.1089/ten.TEC.2017.0133.
7
Translational prospects for human induced pluripotent stem cells.人类诱导多能干细胞的转化前景。
Regen Med. 2010 Jul;5(4):509-19. doi: 10.2217/rme.10.39.
8
Induced pluripotent stem cells: opportunities as research and development tools in 21st century drug discovery.诱导多能干细胞：21 世纪药物发现中作为研究和开发工具的机遇。
Regen Med. 2010 Jul;5(4):557-68. doi: 10.2217/rme.10.36.
9
Modeling human neurological disorders with induced pluripotent stem cells.利用诱导多能干细胞建立人类神经紊乱模型。
J Neurochem. 2014 May;129(3):388-99. doi: 10.1111/jnc.12625. Epub 2013 Dec 15.
10
Human pluripotent stem cells as tools for neurodegenerative and neurodevelopmental disease modeling and drug discovery.人类多能干细胞作为神经退行性疾病和神经发育疾病建模及药物发现的工具。
Expert Opin Drug Discov. 2015 Jun;10(6):615-29. doi: 10.1517/17460441.2015.1037737. Epub 2015 Apr 20.

本文引用的文献

1
Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes.YAP 活性降低可降低杜氏肌营养不良症诱导多能干细胞衍生的心肌细胞的增殖能力。
Sci Rep. 2021 May 14;11(1):10351. doi: 10.1038/s41598-021-89603-8.
2
Anti-senescent drug screening by deep learning-based morphology senescence scoring.基于深度学习的形态衰老评分法进行抗衰老药物筛选。
Nat Commun. 2021 Jan 11;12(1):257. doi: 10.1038/s41467-020-20213-0.
3
The application of convolutional neural network to stem cell biology.卷积神经网络在干细胞生物学中的应用。
Inflamm Regen. 2019 Jul 5;39:14. doi: 10.1186/s41232-019-0103-3. eCollection 2019.
4
Automated Deep Learning-Based System to Identify Endothelial Cells Derived from Induced Pluripotent Stem Cells.基于自动化深度学习的方法鉴定诱导多能干细胞衍生的内皮细胞。
Stem Cell Reports. 2018 Jun 5;10(6):1687-1695. doi: 10.1016/j.stemcr.2018.04.007. Epub 2018 May 10.
5
Clinical Aspects of Type 3 Long-QT Syndrome: An International Multicenter Study.3型长QT综合征的临床特征：一项国际多中心研究
Circulation. 2016 Sep 20;134(12):872-82. doi: 10.1161/CIRCULATIONAHA.116.021823. Epub 2016 Aug 26.
6
Cardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem Cells.使用患者特异性诱导多能干细胞进行心血管疾病建模
Int J Mol Sci. 2015 Aug 12;16(8):18894-922. doi: 10.3390/ijms160818894.
7
Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes.内皮素-1在肥厚型心肌病诱导的多能干细胞衍生心肌细胞中诱导肌原纤维排列紊乱和收缩向量变异性。
J Am Heart Assoc. 2014 Nov 11;3(6):e001263. doi: 10.1161/JAHA.114.001263.
8
Disease characterization using LQTS-specific induced pluripotent stem cells.使用长 QT 综合征特异性诱导多能干细胞进行疾病特征描述。
Cardiovasc Res. 2012 Sep 1;95(4):419-29. doi: 10.1093/cvr/cvs206. Epub 2012 Jun 27.
9
Generation of induced pluripotent stem cells from a small amount of human peripheral blood using a combination of activated T cells and Sendai virus.利用激活的 T 细胞和仙台病毒从小量人外周血中生成诱导多能干细胞。
Nat Protoc. 2012 Mar 15;7(4):718-28. doi: 10.1038/nprot.2012.015.
10
Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome.利用诱导多能干细胞研究 Timothy 综合征的心脏表型。
Nature. 2011 Mar 10;471(7337):230-4. doi: 10.1038/nature09855. Epub 2011 Feb 9.