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单髁与双侧全膝关节置换术20年生存率相似。

Similar 20-year survivorship for single and bilateral total knee arthroplasty.

作者信息

Liu Christina, Varady Nathan, Antonelli Brielle, Thornhill Thomas, Chen Antonia F

机构信息

Department of Orthopaedic Surgery, Brigham and Women's Hospital, 60 Fenwood Road, 2nd Floor, Hale Building for Transformative Medicine, Boston, MA 02115, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

Department of Orthopaedic Surgery, Brigham and Women's Hospital, 60 Fenwood Road, 2nd Floor, Hale Building for Transformative Medicine, Boston, MA 02115, USA.

出版信息

Knee. 2022 Mar;35:16-24. doi: 10.1016/j.knee.2022.02.001. Epub 2022 Feb 14.

Abstract

BACKGROUND

Long-term follow-up after total knee arthroplasty (TKA) is crucial to providing survivorship updates on available TKA implants to guide patient expectations when undergoing TKA. The purpose of this study was to compare implant survivorship between patients undergoing primary single, simultaneous bilateral, and staged bilateral TKA with 15-year minimum follow-up.

METHODS

This retrospective study included 826 patients (n = 1089) who underwent primary single (n = 454), simultaneous bilateral (n = 266), or staged bilateral (n = 369) TKA using a single TKA system by a single surgeon from 1991-2005 with 15-year minimum follow-up. Demographics, clinical variables, and surgical outcomes were collected and compared using Student's t-test, chi-squared tests, or Kaplan-Meier analyses. Reoperation was defined as all surgeries performed on the knee after the index procedure; revision TKA was defined as complete implant exchange. p < 0.05 significant.

RESULTS

Patients in the staged TKA cohort were younger (65.4 years = staged, 67.8 = simultaneous, 67.1 = single, p < 0.019). Women were less likely to receive simultaneous TKAs (22 %vs.29%, p < 0.001). Postoperative range of motion was similar (116.8° = simultaneous, 114.9° = staged, 114.8° = single, p = 0.11). Overall 15-year implant survival based on revision TKA was similar (97.7% = simultaneous, 97.2% = staged, 96.7% = single, p = 0.45). The estimated 15-year reoperation rate was 7.0% (95% CI, 5.5-8.7%). Reoperations were secondary to infection (35.5%), implant wear (26.3%), arthrofibrosis (18.4%), traumatic injuries (10.5%), pain (6.6%), pathologic lesion (1.3%), and avascular necrosis (1.3%).

CONCLUSION

This study demonstrated a high implant survival rate of 95-97% at 20-years after primary single, staged bilateral and simultaneous bilateral TKA. Furthermore, simultaneous bilateral TKAs exhibited similar range of motion, implant survival, and rates of reoperation to staged bilateral and single TKA.

摘要

背景

全膝关节置换术(TKA)后的长期随访对于提供现有TKA植入物的生存率更新至关重要,以便在患者接受TKA时指导其预期。本研究的目的是比较初次单侧、同期双侧和分期双侧TKA患者的植入物生存率,并进行至少15年的随访。

方法

这项回顾性研究纳入了826例患者(共1089膝),这些患者在1991年至2005年间由同一位外科医生使用单一TKA系统接受了初次单侧(n = 454)、同期双侧(n = 266)或分期双侧(n = 369)TKA,并进行了至少15年的随访。收集了人口统计学、临床变量和手术结果,并使用学生t检验、卡方检验或Kaplan-Meier分析进行比较。再次手术定义为初次手术后对膝关节进行的所有手术;翻修TKA定义为完全更换植入物。p < 0.05具有统计学意义。

结果

分期TKA队列中的患者更年轻(分期组65.4岁,同期组67.8岁,单侧组67.1岁,p < 0.019)。女性接受同期TKA的可能性较小(22%对29%,p < 0.001)。术后活动范围相似(同期组116.8°,分期组114.9°,单侧组114.8°,p = 0.11)。基于翻修TKA的总体15年植入物生存率相似(同期组97.7%,分期组97.2%,单侧组96.7%,p = 0.45)。估计的15年再次手术率为7.0%(95%CI,5.5 - 8.7%)。再次手术的原因包括感染(35.5%)、植入物磨损(26.3%)、关节纤维化(18.4%)、创伤性损伤(10.5%)、疼痛(6.6%)、病理性病变(1.3%)和缺血性坏死(1.3%)。

结论

本研究表明,初次单侧、分期双侧和同期双侧TKA术后20年的植入物生存率高达95 - 97%。此外,同期双侧TKA在活动范围、植入物生存率和再次手术率方面与分期双侧和单侧TKA相似。

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