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与年轻患者相比,老年人全膝关节置换术后生存率相似,但功能结果较差:对一种后稳定型植入物进行至少5年随访的分析。

Similar survival rate but lower functional outcomes following TKA in the elderly people compared to younger patients: analysis of a posterior stabilised implant with minimum 5-year follow-up.

作者信息

Deroche Etienne, Batailler Cécile, Shatrov Jobe, Gunst Stanislas, Servien Elvire, Lustig Sébastien

机构信息

Orthopaedic Surgery and Sports Medicine Department, FIFA Medical Center of Excellence, Croix-Rousse Hospital, Lyon University Hospital, Lyon, France.

Sydney Orthopaedic Research Institute (SORI) at Landmark Orthopaedics, 500 Pacific Hwy, St. Leonards, NSW, Australia.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2023 Apr;31(4):1470-1476. doi: 10.1007/s00167-022-07287-7. Epub 2022 Dec 20.

Abstract

BACKGROUND

Literature regarding outcomes in patients over 80 years old after total knee arthroplasty (TKA) is inconsistent. We aimed to compare implant survivorship and functional outcomes between elderly patients (≥ 80 years) and younger patients (< 80 years) following TKA, using a single modern posterior-stabilized (PS) prosthetic design.

METHODS

This is a retrospective cohort study of 80 patients over 80 years old who underwent TKA between January 2015 and December 2016, who were compared with younger patients (60-75 years old) operated during the same period. Patients were matched with a ratio of 1:3 based on logistic regression analysis of gender and body mass index. All patients received the same cemented PS prosthesis with a fixed bearing polyethylene insert, with or without patellar resurfacing. Implant survival and patient-reported outcome measurements were compared between the two groups. At last follow-up, data were available for 41 knees in the elderly group (including 17 patients who died before 5-year follow-up) and 123 knees in the younger group.

RESULTS

Functional results were better at final follow-up in the group < 80 years with a significantly higher Knee Society Function Subscore (88.6 ± 16.9 vs 79.4 ± 22.1, p < 0.01), but no significant differences in Knee Subscore and global Knee Society Score (p > 0.05), nor regarding maximum flexion (121° ± 12 and 117° ± 13, p = 0.08). The implant survivorship was 100.0% after a mean 64.4-month follow-up (range 60-78), without revision requiring removal of the implant in any group. The survival rate without any reoperation was 97.6% (95% CI 93.0-100.0) in the elderly group and 95.9% (95% CI 92.5-99.5) in the younger group (p = 0.64).

CONCLUSION

At a minimum of 5-year follow-up, there was no revision surgery and a very low rate of complications requiring reoperations both in the group over 80 years of age and in the younger population, with the use of a PS prosthesis. The functional results were slightly lower for elderly patients and correlate with the lower functional demands of this population. The indication for TKA, especially with a PS implant, may be encouraged in appropriately selected elderly patients.

LEVEL OF EVIDENCE

III (retrospective cohort study).

摘要

背景

关于全膝关节置换术(TKA)后80岁以上患者预后的文献报道并不一致。我们旨在比较采用单一现代后稳定型(PS)假体设计的老年患者(≥80岁)和年轻患者(<80岁)TKA后的假体生存率和功能预后。

方法

这是一项回顾性队列研究,纳入了2015年1月至2016年12月期间接受TKA的80例80岁以上患者,并与同期手术的年轻患者(60 - 75岁)进行比较。根据性别和体重指数的逻辑回归分析,患者按1:3的比例进行匹配。所有患者均接受相同的骨水泥固定PS假体,带有固定承重聚乙烯内衬,有或无髌骨表面置换。比较两组的假体生存率和患者报告的预后指标。在最后一次随访时,老年组有41例膝关节有数据(包括17例在5年随访前死亡的患者),年轻组有123例膝关节有数据。

结果

在末次随访时,<80岁组的功能结果更好,膝关节协会功能子评分显著更高(88.6±16.9 vs 79.4±22.1,p<0.01),但膝关节子评分和膝关节协会总体评分无显著差异(p>0.05),最大屈曲度也无显著差异(121°±12和117°±13,p = 0.08)。平均64.4个月随访(范围60 - 78个月)后,假体生存率为100.0%,两组均无需要取出假体的翻修手术。老年组无任何再次手术的生存率为97.6%(95%CI 93.0 - 100.0),年轻组为95.9%(95%CI 92.5 - 99.5)(p = 0.64)。

结论

至少5年的随访显示,使用PS假体时,80岁以上组和年轻人群中均无翻修手术,且需要再次手术的并发症发生率极低。老年患者的功能结果略低,这与该人群较低的功能需求相关。对于适当选择的老年患者,可鼓励行TKA,尤其是使用PS假体。

证据级别

III(回顾性队列研究)。

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