Akingbola Olugbenga, Srivastav Sudesh K, Nguyen Michelle, Singh Dinesh, Frieberg Edwin M, Thibodeaux Amy
Division of Pediatric Critical Care, Department of Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana, United States.
Department of Biostatistics and Data Science, Tulane University, New Orleans, Louisiana, United States.
J Pediatr Intensive Care. 2020 Nov 23;11(1):19-25. doi: 10.1055/s-0040-1721657. eCollection 2022 Mar.
We retrospectively reviewed the charts of 180 children sedated for esophagogastroduodenoscopy (EGD) with ketamine or propofol-based regimens at our institution. Pre-EGD diagnoses and American Society of Anesthesiology physical status were similar in all subjects. Onset of action and recovery time for both regimens were not statistically significant ( > 0.05). Mean onset of sedation for all patients was 3.85 ± 3.04 minutes, mean Aldrete score was 6.31 ± 0.61, and mean recovery time was 51.85 ± 31.78 minutes ( > 0.05). Sedation-related adverse events observed include apnea, hypoxemia, bradycardia, hypotension, laryngospasm, skin rash, and wheezing. Deep sedation for pediatric EGD is safe if patients are carefully screened and properly monitored.
我们回顾性地查阅了我院180例接受氯胺酮或丙泊酚方案镇静以进行食管胃十二指肠镜检查（EGD）的儿童病历。所有受试者的EGD术前诊断和美国麻醉医师协会身体状况相似。两种方案的起效时间和恢复时间无统计学差异（P＞0.05）。所有患者的平均镇静起效时间为3.85±3.04分钟，平均Aldrete评分为6.31±0.61，平均恢复时间为51.85±31.78分钟（P＞0.05）。观察到的与镇静相关的不良事件包括呼吸暂停、低氧血症、心动过缓、低血压、喉痉挛、皮疹和喘息。如果对患者进行仔细筛查并进行适当监测，小儿EGD深度镇静是安全的。
