De Proost A, de Meulenaere J
Tijdschr Psychiatr. 2022;64(1):43-47.
The use of antidepressants, specifically selective serotonin reuptake inhibitors, in the treatment of various psychiatric illnesses in children and adolescents has increased throughout the years. Overall, these medications are well tolerated, even though serious side effects have been described. In this case report, we describe the clinical presentation of an adolescent girl who developed a psychotic state after treatment with sertraline in monotherapy. She was diagnosed with major depressive disorder and anxiety symptoms. The psychotic symptoms emerged a few days after the initiation of therapy with sertraline and consisted of visual and auditive hallucinations, just as paranoid delusions. The symptoms disappeared after discontinuation of the sertraline treatment. Based on recent literature, we describe her condition and offer recommendations for the clinical practice.
多年来，抗抑郁药，特别是选择性5-羟色胺再摄取抑制剂，在治疗儿童和青少年各种精神疾病中的使用有所增加。总体而言，这些药物耐受性良好，尽管已有严重副作用的描述。在本病例报告中，我们描述了一名青少年女性在接受舍曲林单药治疗后出现精神病状态的临床表现。她被诊断为重度抑郁症和焦虑症状。精神病症状在舍曲林治疗开始几天后出现，包括视觉和听觉幻觉以及偏执妄想。舍曲林治疗停药后症状消失。基于近期文献，我们描述了她的病情并为临床实践提供建议。
