Department of Forensic Medicine and Toxicology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Poisoning Treatment Center, Ain Shams University Hospitals, Cairo, Egypt.
Drug Alcohol Rev. 2022 Jul;41(5):1109-1118. doi: 10.1111/dar.13443. Epub 2022 Feb 17.
Illicit drug use may result in several emergencies. Hospital emergency data can help to detect new patterns of substance use and high-risk trends of drug use. This epidemiological study aimed to investigate the pattern and outcome of cases with substance use intoxication who presented to Ain Shams University Poisoning Treatment Centre, Cairo, Egypt.
This retrospective study included all cases of acute intoxication due to use/misuse of substances who presented to the centre during the period (2015-2019).
The study included 11 281 cases; young adults (aged 20-40 years) represented the greatest proportion of cases (6519, 57.8%). Males were the predominant gender in all age groups (representing 79.2% of the cases). Tramadol was the most common substance of exposure in all age groups except for children and adolescents where cannabis was the most common one. There were 162 fatalities (1.4% of all cases) and opioids had the greatest case fatality rate.
Tramadol was the most used drug that resulted in acute intoxication, followed by cannabis. A total of 43.6% of the cases of acute intoxications were due to recreational use/misuse of prescription drugs.
非法药物使用可能导致多种急症。医院急诊数据可帮助发现新的药物使用模式和高危药物使用趋势。本项流行病学研究旨在调查埃及开罗艾因夏姆斯大学中毒治疗中心因物质使用/滥用导致中毒并就诊的病例的模式和结局。
本回顾性研究纳入了于研究期间（2015 年至 2019 年）因物质使用/滥用导致急性中毒而到中心就诊的所有病例。
本研究纳入了 11281 例病例；青年（20-40 岁）占比最大（6519 例，占 57.8%）。各年龄段均以男性为主（占病例的 79.2%）。除儿童和青少年外，曲马多在各年龄段均为最常见的暴露物质，而在该年龄段最常见的是大麻。共有 162 例死亡（占所有病例的 1.4%），阿片类药物的病死率最高。
曲马多是导致急性中毒的最常用药物，其次是大麻。43.6%的急性中毒病例是由于消遣性使用/滥用处方药物导致的。
