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[不同产地加工方法对川芎挥发油成分的影响:基于顶空气相色谱 - 质谱联用技术的探究]

[Effects of different field processing methods on volatile components of Chuanxiong Rhizoma: an exploration based on headspace gas chromatography-mass spectrometry].

作者信息

Tang Yi-Na, Guo Jun-Xia, Li Qing-Miao, Yi Jin-Hai

机构信息

Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica,Sichuan Academy of Chinese Medicine Sciences Chengdu 610041, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2022 Feb;47(3):676-683. doi: 10.19540/j.cnki.cjcmm.20210000.300.

DOI:10.19540/j.cnki.cjcmm.20210000.300
PMID:35178950
Abstract

The volatile oil of Chuanxiong Rhizoma(CX) is known as an effective fraction. In order to seek a suitable method for processing CX and its decoction pieces, this study selected 16 volatile components as indices to investigate how different processing methods such as washing/without washing, sun-drying, baking, oven-drying and far-infrared drying at different temperatures affected the quality of CX and its decoction pieces(fresh CX was partially dried, cut into pieces, and then dried) by headspace gas chromatography-mass spectrometry(GC-MS), cluster analysis, principal component analysis and comprehensive weighted scoring. The results showed that the rapid washing before processing did not deteriorate the volatile components of CX. Considering the practical condition of production area, oven-drying was believed to be more suitable than sun-drying, baking, and far-infrared drying. The CX decoction pieces with a thickness of 0.3-0.4 cm were recommended to be oven-dried at 50 ℃. The integrated processing(partial drying, cutting into pieces, and drying) did not cause a significant loss of volatile components. For the fresh CX, the oven-drying at 60 ℃ is preferred. The temperature should not exceed 60 ℃, and drying below 60 ℃ will prolong the processing time, which will produce an unfavorable effect on volatile components. This study has provided the scientific evidence for field processing of CX, which is conducive to realizing the normalization and standardization of CX processing in the production area and stabilizing the quality of CX and its decoction pieces.

摘要

川芎挥发油是其有效部位。为探寻川芎及其饮片适宜的加工方法,本研究选取16种挥发性成分作为指标,采用顶空气相色谱-质谱联用(GC-MS)、聚类分析、主成分分析及综合加权评分法,考察水洗/未水洗、晒干、烘焙、烘干及不同温度远红外干燥等不同加工方法对川芎及其饮片(新鲜川芎经部分干燥、切片后再干燥)质量的影响。结果表明,加工前快速水洗未使川芎挥发性成分劣变。结合产地实际情况,烘干较晒干、烘焙及远红外干燥更适宜。建议厚度为0.3 - 0.4 cm的川芎饮片在50℃烘干。一体化加工(部分干燥、切片及干燥)未导致挥发性成分显著损失。对于新鲜川芎,60℃烘干为宜,温度不宜超过60℃,低于60℃干燥会延长加工时间,对挥发性成分产生不利影响。本研究为川芎产地加工提供了科学依据,有利于实现产地川芎加工的规范化、标准化,稳定川芎及其饮片的质量。

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