van Beuningen D
Strahlenther Onkol. 1986 Apr;162(4):223-5.
Data from the literature on total body irradiation are reported. The biological concept of fractionation of TBI is reviewed. The therapeutic gain of fractionated single dose as compared single dose to irradiation is explained. However, other data from Song et al. show that repair capacity of hemopoietic or leukemic cells may be underestimated. More data with fractionation experiments are needed. The significance of repopulation between fractionation doses is unknown. The interaction of TBI and preceding chemotherapy should be studied in more detail.
报告了有关全身照射的文献数据。回顾了全身照射分次照射的生物学概念。解释了分次单剂量照射与单次剂量照射相比的治疗增益。然而，宋等人的其他数据表明，造血或白血病细胞的修复能力可能被低估了。需要更多分次照射实验的数据。分次照射剂量之间再增殖的意义尚不清楚。应更详细地研究全身照射与先前化疗的相互作用。
