Gidaiatov A A, Abasov I T, Aliev M G, Guseĭnov Sh G
Ter Arkh. 1986;58(2):105-6.
The concentration of somatotropic hormone (STH) was measured by radioimmunoassay in 108 patients with acute and chronic pancreatitis and in 15 healthy persons. In addition, to study the reserve capacity of the somatotropic function of the pituitary, insulin hypoglycemia was employed. It was established that during exacerbation, the pancreatitis patients manifested an increase in the hormone content. In the patients suffering from acute pancreatitis, the STH level returned to normal following treatment. In chronic pancreatitis, the hormone concentration remained elevated after treatment. No correlation was discovered between alterations in the STH level and the activity of pancreatic enzymes. The data obtained point to a definite role of STH in the pathogenesis of chronic pancreatitis.
采用放射免疫分析法对108例急慢性胰腺炎患者及15名健康人进行生长激素(STH)浓度测定。此外,为研究垂体生长激素功能的储备能力,采用了胰岛素低血糖试验。结果发现,在病情加重期,胰腺炎患者的激素含量增加。急性胰腺炎患者经治疗后STH水平恢复正常。慢性胰腺炎患者治疗后激素浓度仍升高。未发现STH水平变化与胰酶活性之间存在相关性。所获数据表明STH在慢性胰腺炎发病机制中具有一定作用。