重复剖宫产中使用组织粘合剂或缝线进行皮肤缝合的美容效果：一项随机对照试验。
Cosmetic outcomes of skin closure with tissue adhesive or staples in repeated cesarean section: A randomized controlled trial.
机构信息
Department of Obstetrics and Gynecology, "Filippo Del Ponte" Hospital, University of Insubria, Varese, Italy.
Department of Obstetrics and Gynecology, "Filippo Del Ponte" Hospital, University of Insubria, Varese, Italy.
出版信息
Eur J Obstet Gynecol Reprod Biol. 2022 Apr;271:112-116. doi: 10.1016/j.ejogrb.2022.02.009. Epub 2022 Feb 14.
OBJECTIVE
To compare scar quality associated with metal staples or tissue adhesive for closure of the skin incision at repeat cesarean delivery (CD).
STUDY DESIGN
Single-center Randomized Controlled Trial (ClinicalTrial.gov ID: NCT04302597), including women undergoing repeat CD using metal staples or 2- octylcyanoacrylate for closure of the skin incision. Patients were randomized to have skin closure following CD with either staples or tissue adhesive. Scar quality was evaluated 2 and 6 months postoperatively using the Vancouver Scar Scale, the Patient and Observer Scar Assessment Scale (POSAS), and a visual analog scale.
RESULTS
Of the 66 patients who were recruited, 55 successfully completed the study. The duration of surgery was comparable in both groups. A partial wound dehiscence occurred in one patient who had tissue adhesive closure. No difference in subjective and objective scar cosmesis rating was found between tissue adhesive and staples groups at either 2 months or 6 months.
CONCLUSIONS
In women undergoing CD, stapled wounds and those closed with tissue adhesive result in equivalent cosmetic appearance of the scar.
目的
比较在重复剖宫产时使用金属钉或组织胶闭合皮肤切口的瘢痕质量。
研究设计
单中心随机对照试验（ClinicalTrials.gov 注册号：NCT04302597），纳入接受重复剖宫产并使用金属钉或 2-辛基氰基丙烯酸酯闭合皮肤切口的女性。患者随机分为采用金属钉或组织胶闭合皮肤切口。术后 2 个月和 6 个月使用温哥华瘢痕量表、患者和观察者瘢痕评估量表（POSAS）和视觉模拟评分评估瘢痕质量。
结果
共招募了 66 名患者，其中 55 名成功完成了研究。两组手术时间相当。1 名使用组织胶闭合的患者出现部分伤口裂开。在术后 2 个月和 6 个月时，组织胶组和金属钉组的主观和客观瘢痕美容评分均无差异。
结论
在接受剖宫产的女性中，金属钉缝合的伤口和组织胶闭合的伤口的瘢痕外观相当。
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