Patriquin H, Robitaille P
AJR Am J Roentgenol. 1986 Jun;146(6):1253-6. doi: 10.2214/ajr.146.6.1253.
The Anderson-Carr theory of renal-stone formation, based on cadaver studies, postulates the aggregation of calcium at the tips and margins of the renal pyramid. Progressive calcium deposition is followed by the formation of calcium plaques, which may perforate the calyx and form a nidus for further stone growth. This theory has not been demonstrated in vivo. We studied 50 children with conditions leading to nephrocalcinosis with renal sonography. Seven of these had high-resolution CT. Twenty-four positive sonographic examinations were used to study patterns of calcium deposition in the kidney. Nephrocalcinosis was confined to the medulla and was found at the margins of the pyramid, at the fornix, or throughout the entire pyramid. Five children showed calcium plaques in or near the calyx. The sonographic pattern identified appears to provide an in vivo demonstration of the Anderson-Carr progression of renal-stone formation.
基于尸体研究的安德森 - 卡尔肾结石形成理论假定钙在肾锥体尖端和边缘聚集。钙的逐步沉积之后是钙斑的形成，钙斑可能会穿透肾盏并形成结石进一步生长的核心。该理论尚未在体内得到证实。我们用肾脏超声对50名患有导致肾钙质沉着症疾病的儿童进行了研究。其中7名儿童进行了高分辨率CT检查。24次超声检查结果呈阳性的病例用于研究肾脏中钙沉积的模式。肾钙质沉着症局限于髓质，见于锥体边缘、穹窿部或整个锥体。5名儿童在肾盏内或其附近显示有钙斑。所确定的超声模式似乎为安德森 - 卡尔肾结石形成进展提供了体内证据。
