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梅尼埃病患者眩晕发作时的内淋巴积水磁共振成像

Endolymphatic Hydrops Magnetic Resonance Imaging in Menire's Disease Patients on a Vertigo Attack.

作者信息

Chen Wei, Geng Yue, Niu Yue, Lin Mengyan, Lin Naier, Sha Yan

机构信息

Department of Radiology, Eye & ENT Hospital of Fudan University.

Shanghai Institute of Medical Imaging, Fudan University, Shanghai, China.

出版信息

Otol Neurotol. 2022 Apr 1;43(4):489-493. doi: 10.1097/MAO.0000000000003474.

DOI:10.1097/MAO.0000000000003474
PMID:35184071
Abstract

OBJECTIVE

To investigate the characteristics of endolymphatic hydrops (EH) in Menire's disease (MD) patient on a vertigo attack.

STUDY DESIGN

Prospective study.

SETTING

Tertiary referral center.

PATIENTS

Thirty-six MD patients underwent the enhanced magnetic resonance imaging (MRI) examinations of the inner ear on a vertigo attack were enrolled.

MAIN OUTCOME MEASURES

All patients met the diagnostic criteria for MD and underwent intravenous gadolinium injection 4 hours before the MRI examinations. The MRI examinations were performed in MD patients on a vertigo attack.

RESULTS

Various degrees of vestibular EH appeared in almost all affected ears (2 ears had no EH, 11 ears had mild EH, 26 ears had significant EH). The positive rate of vestibular EH was 37/39 (94.9%). Cochlear EH occurred in 29 ears among 39 affected ears (17 ears had mild EH, 12 ears had significant EH).

CONCLUSION

MRI with intravenous gadolinium injection can provide a better assessment of EH in MD patient on a vertigo attack. Vestibular EH seems to be closely related with the vertigo attacks in MD patients, which needs further study.

摘要

目的

探讨梅尼埃病(MD)患者眩晕发作时内淋巴积水(EH)的特征。

研究设计

前瞻性研究。

研究地点

三级转诊中心。

患者

纳入36例在眩晕发作时接受内耳增强磁共振成像(MRI)检查的MD患者。

主要观察指标

所有患者均符合MD诊断标准,并在MRI检查前4小时静脉注射钆剂。对MD患者在眩晕发作时进行MRI检查。

结果

几乎所有患耳均出现不同程度的前庭EH(2耳无EH,11耳为轻度EH,26耳为重度EH)。前庭EH阳性率为37/39(94.9%)。39例患耳中有29耳出现耳蜗EH(17耳为轻度EH,12耳为重度EH)。

结论

静脉注射钆剂的MRI能更好地评估MD患者眩晕发作时的EH情况。前庭EH似乎与MD患者的眩晕发作密切相关,这需要进一步研究。

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引用本文的文献

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Potential Application of Hydrops MR Imaging: A Systematic Review.积水磁共振成像的潜在应用:系统评价。
J Otolaryngol Head Neck Surg. 2024 Jan-Dec;53:19160216241250350. doi: 10.1177/19160216241250350.
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Functional and Molecular Markers for Hearing Loss and Vertigo Attacks in Meniere's Disease.梅尼埃病听力损失和眩晕发作的功能和分子标志物。
Int J Mol Sci. 2023 Jan 28;24(3):2504. doi: 10.3390/ijms24032504.