Senior C C, Steigrad S J
Am J Obstet Gynecol. 1986 May;154(5):1004-8. doi: 10.1016/0002-9378(86)90738-6.
An open, randomized study to compare the effectiveness of triple-dose cefoxitin with the effectiveness of cephradine-tinidazole and with the result of nontreatment in patients undergoing abdominal hysterectomy was conducted from July 1983 to July 1984. One hundred ninety-nine patients were enrolled: 66 untreated control patients, 69 patients in the cephradine-tinidazole--treated group, and 64 patients in the cefoxitin-treated group. No significant differences were present in relation to age, pathologic condition, length of operation, blood loss, or length of hospital stay. That patients in both treatment groups had a lower incidence of postoperative febrile morbidity was not statistically significant.
1983年7月至1984年7月，开展了一项开放性随机研究，比较三剂量头孢西丁与头孢拉定-替硝唑的疗效以及腹部子宫切除患者不治疗的结果。共纳入199例患者：66例未治疗的对照患者、69例头孢拉定-替硝唑治疗组患者和64例头孢西丁治疗组患者。在年龄、病理状况、手术时间、失血量或住院时间方面无显著差异。两个治疗组患者术后发热发病率较低，但无统计学意义。
