在刺激过程中，视觉皮层中的心血管搏动性在血氧水平依赖反应之前增加。
Cardiovascular Pulsatility Increases in Visual Cortex Before Blood Oxygen Level Dependent Response During Stimulus.
作者信息
Huotari Niko, Tuunanen Johanna, Raitamaa Lauri, Raatikainen Ville, Kananen Janne, Helakari Heta, Tuovinen Timo, Järvelä Matti, Kiviniemi Vesa, Korhonen Vesa
机构信息
Oulu Functional Neuro Imaging Group, Research Unit of Medical Imaging Physics and Technology (MIPT), University of Oulu, Oulu, Finland.
Department of Diagnostic Radiology, Medical Research Center (MRC), Oulu University Hospital, Oulu, Finland.
出版信息
Front Neurosci. 2022 Feb 3;16:836378. doi: 10.3389/fnins.2022.836378. eCollection 2022.
The physiological pulsations that drive tissue fluid homeostasis are not well characterized during brain activation. Therefore, we used fast magnetic resonance encephalography (MREG) fMRI to measure full band (0-5 Hz) blood oxygen level-dependent (BOLD) signals during a dynamic visual task in 23 subjects. This revealed brain activity in the very low frequency (BOLD) as well as in cardiac and respiratory bands. The cardiovascular hemodynamic envelope (CHe) signal correlated significantly with the visual BOLD response, considered as an independent signal source in the V1-V2 visual cortices. The CHe preceded the canonical BOLD response by an average of 1.3 (± 2.2) s. Physiologically, the observed CHe signal could mark increased regional cardiovascular pulsatility following vasodilation.
在大脑激活过程中，驱动组织液稳态的生理搏动尚未得到充分表征。因此，我们使用快速磁共振脑成像（MREG）功能磁共振成像（fMRI）来测量23名受试者在动态视觉任务期间的全频段（0-5Hz）血氧水平依赖（BOLD）信号。这揭示了极低频（BOLD）以及心脏和呼吸频段的大脑活动。心血管血液动力学包络（CHe）信号与视觉BOLD反应显著相关，视觉BOLD反应被视为V1-V2视觉皮层中的独立信号源。CHe比典型的BOLD反应平均提前1.3（±2.2）秒。从生理角度来看，观察到的CHe信号可能标志着血管舒张后局部心血管搏动性增加。
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