Clouse R E, Alpers D H
Annu Rev Med. 1986;37:283-95. doi: 10.1146/annurev.me.37.020186.001435.
The definition of psychiatric illness by specific criteria has provided a new method for examining the relationship of certain gastrointestinal (GI) diseases to psychiatric disorder. Using this technique, researchers have found that rates of psychiatric diagnosis in patients with certain functional GI syndromes and Crohn's disease exceed those found in the general population and in comparably ill control groups. Timing of onset of both sets of symptoms (GI and psychiatric) suggests that the functional syndromes generally follow or coincide with the onset of psychiatric symptoms, whereas the onset of Crohn's disease is more independent. A relationship of psychiatric illness to other GI disease is suspected based on results of psychometric testing or on less structured attempts at psychiatric diagnosis employed in earlier studies. Psychiatric diagnosis by criteria definition may play an important role in more clearly understanding any relationship of psychiatric disorder to somatic GI disease as the applications of this scientific technique are expanded.
通过特定标准对精神疾病进行定义，为研究某些胃肠道（GI）疾病与精神障碍之间的关系提供了一种新方法。运用这项技术，研究人员发现，某些功能性胃肠综合征和克罗恩病患者的精神疾病诊断率高于普通人群以及病情相当的对照组。两组症状（胃肠道症状和精神症状）的发作时间表明，功能性综合征通常在精神症状发作之后出现或与之同时出现，而克罗恩病的发作则较为独立。基于心理测量测试结果或早期研究中采用的结构化程度较低的精神疾病诊断尝试，人们怀疑精神疾病与其他胃肠道疾病之间存在关联。随着这项科学技术应用范围的扩大，依据标准定义进行精神疾病诊断可能在更清晰地理解精神障碍与躯体性胃肠道疾病之间的任何关系方面发挥重要作用。
