Qamar Mohammad Aadil, Martins Russell Seth, Dhillon Rubaid Azhar, Tharwani Areeba, Irfan Omar, Suriya Qosain Fatima, Rizwan Wajiha, Khan Javaid Ahmed, Zubairi Ali Bin Sarwar
Ziauddin University, Karachi, Pakistan.
Medical College, Aga Khan University, Karachi, Pakistan.
Ann Med Surg (Lond). 2022 Mar;75:103361. doi: 10.1016/j.amsu.2022.103361. Epub 2022 Feb 11.
There remains scarcity of literature regarding the patient's health status post-COVID-19 infection. This study analyzes the prevalence of residual symptoms and quality of life (QoL) after COVID-19.
An anonymous online survey was administrated in Pakistan from November 2020 to April 2021 in COVID-19 survivors. The questionnaire used the 12-Item Short Form Health Survey (SF-12) to assess mental and physical QoL. Multivariate linear regression was used to explore factors associated with mental and physical QoL scores.
A total of 331 COVID-19 survivors participated in our survey. Around 42.0% of the cohort reported within 1-3 months of diagnosis of COVID-19. The common residual symptoms were body aches (39.9%), low mood (32.6%), and cough (30.2%). Better physical QoL was associated with being male (adjusted beta: 3.328) and having no residual symptoms (6.955). However, suffering from nausea/vomiting during initial COVID-19 infection (-4.026), being admitted to the ICU during COVID-19 infection (-9.164), and suffering from residual body aches (-5.209) and low mood (-2.959) was associated with poorer QoL. Better mental QoL was associated with being asymptomatic during initial COVID-19 infection (6.149) and post-COVID (6.685), while experiencing low mood post-COVID was associated with poorer mental QoL (-8.253 [-10.914, -5.592]).
Despite presumed "recovery" from COVID-19, patients still face a wide range of residual symptoms months after initial infection, which contributes towards poorer QoL. Healthcare professionals must remain alert to the long-lasting effects of COVID-19 infection and aim to address them appropriately to improve patients' QoL.
关于新冠病毒感染后患者健康状况的文献仍然匮乏。本研究分析了新冠病毒感染后残留症状的患病率和生活质量（QoL）。
2020年11月至2021年4月在巴基斯坦对新冠病毒感染幸存者进行了一项匿名在线调查。问卷使用12项简短健康调查问卷（SF-12）来评估心理和生理生活质量。采用多元线性回归来探讨与心理和生理生活质量得分相关的因素。
共有331名新冠病毒感染幸存者参与了我们的调查。约42.0%的队列在新冠病毒感染诊断后的1至3个月内报告情况。常见的残留症状有身体疼痛（39.9%）、情绪低落（32.6%）和咳嗽（30.2%）。较好的生理生活质量与男性（调整后的β系数：3.328）和无残留症状（6.955）相关。然而，在初次感染新冠病毒期间出现恶心/呕吐（-4.026）、在新冠病毒感染期间入住重症监护病房（-9.164）以及出现残留身体疼痛（-5.209）和情绪低落（-2.959）与较差的生活质量相关。较好的心理生活质量与初次感染新冠病毒期间无症状（6.149）和新冠病毒感染后无症状（6.685）相关，而新冠病毒感染后情绪低落与较差的心理生活质量相关（-8.253[-10.914，-5.592]）。
尽管假定从新冠病毒感染中“康复”，但患者在初次感染数月后仍面临广泛的残留症状，这导致生活质量较差。医疗保健专业人员必须对新冠病毒感染的长期影响保持警惕，并旨在适当地解决这些问题以改善患者的生活质量。
