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评估和描述新冠病毒感染后的表现。

Assessment and characterisation of post-COVID-19 manifestations.

机构信息

Clinical Pharmacy Department, Faculty of Pharmacy, Fayoum University, Fayoum, Egypt.

Department of Neurology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.

出版信息

Int J Clin Pract. 2021 Mar;75(3):e13746. doi: 10.1111/ijcp.13746. Epub 2020 Nov 3.

DOI:10.1111/ijcp.13746
PMID:32991035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7536922/
Abstract

BACKGROUND

Post-COVID-19 symptoms and diseases appeared on many survivors from COVID-19 which are similar to that of the post-severe acute respiratory syndrome (SARS) fatigue. Hence, the study aims to investigate and characterise the manifestations which appear after eradication of the coronavirus infection and its relation to disease severity.

METHOD

About 287 survivors from COVID-19 were included in the study, each received a questionnaire divided into three main parts starting from subjects' demographic data, data about the COVID-19 status and other comorbidities of the subject, and finally data about post-COVID-19 manifestations. Response surface plots were produced to visualise the link between several factors.

RESULTS

Only 10.8% of all subjects have no manifestation after recovery from the disease while a large percentage of subjects suffered from several symptoms and diseases. The most common symptom reported was fatigue (72.8%), more critical manifestations like stroke, renal failure, myocarditis and pulmonary fibrosis were reported by a few percent of the subjects. There was a relationship between the presence of other comorbidities and severity of the disease. Also, the severity of COVID-19 was related to the severity of post-COVID-19 manifestations.

CONCLUSION

The post-COVID-19 manifestation is largely similar to the post-SARS syndrome. All subjects recovered from COVID-19 should undergo long-term monitoring for evaluation and treatment of symptoms and conditions that might be precipitated with the new coronavirus infection.

摘要

背景

许多 COVID-19 幸存者出现了类似于严重急性呼吸综合征(SARS)后疲劳的 COVID-19 后症状和疾病。因此,本研究旨在调查和描述冠状病毒感染消除后出现的表现及其与疾病严重程度的关系。

方法

本研究纳入了 287 名 COVID-19 幸存者,每位患者均接受了一份问卷,问卷分为三个主要部分,分别是受试者的人口统计学数据、COVID-19 状况和其他合并症数据,以及 COVID-19 后表现数据。制作响应面图以可视化几个因素之间的联系。

结果

只有 10.8%的受试者在从疾病中康复后没有任何表现,而大部分受试者都患有几种症状和疾病。报告最多的常见症状是疲劳(72.8%),少数患者报告了更严重的表现,如中风、肾衰竭、心肌炎和肺纤维化。其他合并症的存在与疾病的严重程度有关。此外,COVID-19 的严重程度与 COVID-19 后的表现严重程度有关。

结论

COVID-19 后的表现与 SARS 后综合征非常相似。所有从 COVID-19 中康复的患者都应接受长期监测,以评估和治疗可能因新的冠状病毒感染而引发的症状和疾病。

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