急性淋巴细胞白血病中超越Hyper-CVAD方案：SOHO 2021会议亮点 - Suppr

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Beyond Hyper-CVAD in ALL: Highlights From SOHO 2021.

出版信息

J Adv Pract Oncol. 2022 Jan;13(Suppl 1):9-11. doi: 10.6004/jadpro.2022.13.1.10. Epub 2022 Feb 2.

DOI:10.6004/jadpro.2022.13.1.10

PMID:35186401

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8824280/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a2/8824280/a2f5cc141fa8/jadpro.2022.13.1.10g001.jpg

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Hyper-CVAD regimen in combination with ofatumumab as frontline therapy for adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia: a single-arm, phase 2 trial.Hyper-CVAD方案联合奥法妥木单抗作为费城染色体阴性B细胞急性淋巴细胞白血病成人患者的一线治疗：一项单臂2期试验。

Lancet Haematol. 2020 Jul;7(7):e523-e533. doi: 10.1016/S2352-3026(20)30144-7.

Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: long-term follow-up of a single-centre, phase 2 study.Hyper-CVAD与波纳替尼联合作为费城染色体阳性急性淋巴细胞白血病患者的一线治疗：一项单中心2期研究的长期随访

Lancet Haematol. 2018 Dec;5(12):e618-e627. doi: 10.1016/S2352-3026(18)30176-5.

Chemoimmunotherapy with inotuzumab ozogamicin combined with mini-hyper-CVD, with or without blinatumomab, is highly effective in patients with Philadelphia chromosome-negative acute lymphoblastic leukemia in first salvage.在首次挽救性化疗中，采用奥加米星单抗联合 mini-hyper-CVD 的化疗免疫治疗，联合或不联合blinatumomab，对费城染色体阴性急性淋巴细胞白血病患者具有高度疗效。

Cancer. 2018 Oct 15;124(20):4044-4055. doi: 10.1002/cncr.31720. Epub 2018 Oct 11.

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