Mitsogiannis Iraklis, Tzelves Lazaros, Mitsogianni Maria, Vgenopoulou Stephanie
2nd Department of Urology, Sismanoglio General Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Department of Pathology, Sismanoglio General Hospital, Athens, GRC.
Cureus. 2022 Jan 16;14(1):e21281. doi: 10.7759/cureus.21281. eCollection 2022 Jan.
Lymphoepithelioma-like carcinoma of the urinary bladder is a rare variant of infiltrating urothelial carcinoma. Diagnostic and therapeutic manipulations are not yet standardised, due to the rarity of the tumour, with surgery and chemotherapy being reported as potential therapeutic options. We report on a case of lymphoepithelioma-like carcinoma of the bladder in a 93-year-old female patient and discuss the pathological features and therapeutic options of the neoplasm. Due to her increased age and associated comorbidities such as hypertension, diabetes mellitus and ischemic heart disease, the patient was treated with transurethral resection of the tumour and subsequent cisplatin-based chemotherapy but unfortunately died of chemotherapy-related complications.
膀胱淋巴上皮瘤样癌是浸润性尿路上皮癌的一种罕见变体。由于该肿瘤罕见,诊断和治疗操作尚未标准化,手术和化疗被报道为潜在的治疗选择。我们报告一例93岁女性患者的膀胱淋巴上皮瘤样癌病例,并讨论该肿瘤的病理特征和治疗选择。由于患者年龄增加以及伴有高血压、糖尿病和缺血性心脏病等合并症,该患者接受了经尿道肿瘤切除术及随后的顺铂化疗,但不幸死于化疗相关并发症。