Saini Swati, Garg Monika, Goyal Shaina, Chaudhary Anita
Department of Pathology, Government Medical College, Patiala, Punjab, India.
J Lab Physicians. 2021 Nov 23;14(1):84-86. doi: 10.1055/s-0041-1736481. eCollection 2022 Mar.
Lymphoepithelioma-like carcinoma of the urinary bladder is a rare variant of urothelial carcinoma that was first described by Zukerberg in 1991 and confirmed as a type of urothelial carcinoma by the WHO classification of the urinary system tumors. A 63-year-old man presented with the chief complaint of gross hematuria for 2 months. Sections from transurethral resection of the bladder revealed urothelial carcinoma. A radical cystoprostatectomy was performed and a final histopathological examination revealed high-grade muscle-invasive urothelial carcinoma, lymphoepithelial variant. The patient has been receiving adjuvant chemotherapy with no recurrence reported to date. This is the third case reported in India to date to the best of our knowledge. Owing to its rare presentation, no definite treatment guidelines have been established for this entity. Various studies from the English literature suggest a conservative approach.
膀胱淋巴上皮瘤样癌是尿路上皮癌的一种罕见变体,于1991年由祖克伯格首次描述,并被世界卫生组织泌尿系统肿瘤分类确认为尿路上皮癌的一种类型。一名63岁男性以肉眼血尿2个月为主诉就诊。经尿道膀胱切除术的切片显示为尿路上皮癌。进行了根治性膀胱前列腺切除术,最终组织病理学检查显示为高级别肌层浸润性尿路上皮癌,淋巴上皮样变体。该患者一直在接受辅助化疗,迄今为止未报告复发情况。据我们所知,这是印度迄今为止报道的第三例病例。由于其罕见的表现,尚未为该实体制定明确的治疗指南。来自英文文献的各种研究表明应采取保守方法。