Yu Ann Kashmer D, Kilic Fatma, Dhawan Raghav, Sidhu Rubani, Elazrag Shahd E, Bijoora Manaal, Sekhar Supriya, Makaram Ravinarayan Surabhi, Mohammed Lubna
Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Plastic and Reconstructive Surgery, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Cureus. 2022 Jan 17;14(1):e21333. doi: 10.7759/cureus.21333. eCollection 2022 Jan.
High-intensity interval training (HIIT), an exercise training modality of cardiac rehabilitation, has shown growing evidence of improving cardiovascular patients' prognosis and health outcomes. This study aimed to identify and summarize the effects of HIIT in heart failure (HF) patients, heart transplantation (HTx) recipients, and HF patients before and after HTx. This systematic review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. For the past five years, a systematic search was done using PubMed, PubMed Central, Cochrane, Google Scholar, and ScienceDirect databases on September 15, 2021. Studies were selected based on the following predefined eligibility criteria: English-language randomized controlled trials (RCTs), observational studies, systematic reviews, and meta-analyses, which included HF patients and HTx patients, and assessment of effects HIIT. The relevant data were extracted to a predefined template. Consequently, quality assessment was done using each study's most commonly used assessment tools. The initial search generated 551 studies. Nine studies were included in the final selection - four RCTs, one cohort, one quasi-experimental study, two systematic reviews with meta-analyses, and one narrative review. HIIT was found to be generally superior or similar with other exercise training on VO peak, heart rate, LVEF, cardiac biomarkers, vascular function, blood pressure, body composition, and adverse events in HF patients and the aforementioned with QoL among HTx recipients. Data on cardiac remodeling and QoL of HF patients were inconclusive.
高强度间歇训练（HIIT）是心脏康复的一种运动训练方式，越来越多的证据表明它能改善心血管疾病患者的预后和健康状况。本研究旨在确定并总结HIIT对心力衰竭（HF）患者、心脏移植（HTx）受者以及HTx前后的HF患者的影响。本系统评价基于系统评价和Meta分析的首选报告项目（PRISMA）指南。在过去五年中，于2021年9月15日使用PubMed、PubMed Central、Cochrane、谷歌学术和ScienceDirect数据库进行了系统检索。根据以下预先定义的纳入标准选择研究：英文随机对照试验（RCT）、观察性研究、系统评价和Meta分析，其中包括HF患者和HTx患者，以及对HIIT效果的评估。将相关数据提取到预先定义的模板中。因此，使用每项研究最常用的评估工具进行质量评估。初步检索产生了551项研究。最终纳入9项研究——4项RCT、1项队列研究、1项半实验研究、2项带有Meta分析的系统评价和1项叙述性综述。结果发现，在HF患者的最大摄氧量、心率、左心室射血分数、心脏生物标志物、血管功能、血压、身体成分和不良事件方面，HIIT总体上优于或类似于其他运动训练，在HTx受者的生活质量方面也是如此。关于HF患者心脏重塑和生活质量的数据尚无定论。
