Department of Neurological Sciences, University of Vermont, Robert Larner MD College of Medicine and the University of Vermont Medical Center, Burlington, VT.
J Clin Neuromuscul Dis. 2022 Mar 1;23(3):119-123. doi: 10.1097/CND.0000000000000365.
Respiratory failure in Guillain-Barre syndrome (GBS) is common. Forced vital capacity (FVC) is the gold standard for monitoring respiratory muscle strength in GBS. In some clinical situations, FVC testing could be delayed or unavailable, thus there is a need for accurate, fast, and device-free bedside respiratory evaluation.
We examined neck flexion strength in 23 GBS patients as a possible predictor of the need for subsequent intubation and as a predictor of FVC change.
Intubation was required by 100% of patients with neck flexion strength of Medical Research Council grade ≤3. A correlation between neck flexion strength and FVC could not be determined.
Significant weakness of neck flexion (Medical Research Council grade ≤3) at the time of admission correlates with poor respiratory status as measured by the need for intubation in patients with GBS.
吉兰-巴雷综合征（GBS）常伴有呼吸衰竭。用力肺活量（FVC）是监测 GBS 患者呼吸肌力量的金标准。在某些临床情况下，FVC 检测可能会延迟或无法进行，因此需要准确、快速且无需设备的床边呼吸评估。
我们研究了 23 例 GBS 患者的颈屈肌力量，以评估其是否可能需要后续插管，以及是否可以预测 FVC 的变化。
颈屈肌力量为英国医学研究理事会（Medical Research Council）分级≤3 的患者 100%需要插管。颈屈肌力量与 FVC 之间无相关性。
入院时颈屈肌明显无力（英国医学研究理事会分级≤3）与 GBS 患者需要插管的呼吸状态不良相关。
