Imura T, Yamamoto K, Kanamori K, Mikami T, Yasuda H
Cardiovasc Res. 1986 Mar;20(3):208-14. doi: 10.1093/cvr/20.3.208.
A new echo tracking device linked to real time ultrasonic B mode equipment was developed to measure non-invasively the elastic properties of the human abdominal aorta. Pulsatile diameter change and mean diameter of the abdominal aorta were measured in 61 subjects with this ultrasonic device. Strain and pressure-strain elastic modulus Ep were calculated from pulsatile diameter change, diameter, and pulse pressure obtained by the auscultatory method. Strain significantly decreased with age; 0.076(0.024) (mean(SD)) in group 1 (20 young adults below the age of 35 years); 0.048(0.024) in group 2 (21 middle aged subjects between the ages of 35 and 60 years); and 0.030(0.010) in group 3 (20 elderly subjects over the age of 60 years). Ep values were 0.99(0.34) X 10(5), 1.55(0.68) X 10(5), and 3.80(2.05) X 10(5) N X m-2 in groups 1, 2, and 3 respectively. Ep in group 3 was significantly higher than in groups 1 and 2. The regression equation relating Ep to age was Ep = (-0.72 + 0.058 X age) X 10(5) N X m-2 (r = 0.73). The Ep value and its age related increase agreed with the findings in postmortem arteries. The elastic properties of the abdominal aorta could, therefore, be determined non-invasively by this ultrasonic method.
一种与实时超声B型设备相连的新型回声跟踪装置被研发出来，用于非侵入性地测量人体腹主动脉的弹性特性。使用该超声设备对61名受试者的腹主动脉搏动直径变化和平均直径进行了测量。根据搏动直径变化、直径以及通过听诊法获得的脉压计算应变和压力-应变弹性模量Ep。应变随年龄显著降低；第1组（20名年龄在35岁以下的年轻成年人）为0.076(0.024)（均值(标准差)）；第2组（21名年龄在35至60岁之间的中年受试者）为0.048(0.024)；第3组（20名年龄在60岁以上的老年受试者）为0.030(0.010)。第1、2、3组的Ep值分别为0.99(0.34)×10(5)、1.55(0.68)×10(5)和3.80(2.05)×10(5) N×m-2。第3组的Ep显著高于第1组和第2组。将Ep与年龄相关联的回归方程为Ep = (-0.72 + 0.058×年龄)×10(5) N×m-2（r = 0.73）。Ep值及其与年龄的相关性增加与死后动脉的研究结果一致。因此，通过这种超声方法可以非侵入性地确定腹主动脉的弹性特性。
