Imura T
Hokkaido Igaku Zasshi. 1985 Sep;60(5):653-61.
For the purpose of the non-invasive measurement of the elastic properties of human abdominal aorta, we developed high sensitive measurement system of small displacement of tissue. This system consists of phase locked echo tracking loop combined with conventional B-mode imaging. The sensitivity to displacement in the model experiment was in the order of micro meter. Pressure strain elastic modulus (Ep) and stiffness parameter (beta) of abdominal aorta were calculated by our equipment in 61 persons, which were subdivided into 3 age groups, the young group (20 persons less than 35 yrs.), the middle aged group (21 persons between 35 yrs. and 60 yrs.), and the old group (20 persons more than 60 yrs.). Ep in the young group was 0.99 +/- 0.34 X 10(6) dynes/cm2, the middle aged group 1.55 +/- 0.68 X 10(6) dynes/cm2, the old group 3.80 +/- 2.05 X 10(6) dynes/cm2. Beta in the young group was 9.3 +/- 3.3, the middle aged group 12.0 +/- 4.5, the old group 27.6 +/- 14.0. The values of Ep and beta in the old group were significantly different from those in the young group and the middle group. Moreover large deviation of the both values was showed within the old group. The influence of aging on the elastic properties of abdominal aorta was found with large individual variation in relation to the progression of the sclerotic change.
为了对人体腹主动脉的弹性特性进行无创测量，我们开发了一种高灵敏度的组织小位移测量系统。该系统由锁相回波跟踪环路与传统B模式成像相结合组成。在模型实验中，其对位移的灵敏度达到微米量级。我们的设备对61名受试者的腹主动脉压力应变弹性模量（Ep）和硬度参数（β）进行了计算，这些受试者被分为3个年龄组：青年组（20名年龄小于35岁）、中年组（21名年龄在35岁至60岁之间）和老年组（20名年龄大于60岁）。青年组的Ep为0.99±0.34×10⁶达因/平方厘米，中年组为1.55±0.68×10⁶达因/平方厘米，老年组为3.80±2.05×10⁶达因/平方厘米。青年组的β为9.3±3.3，中年组为12.0±4.5，老年组为27.6±14.0。老年组的Ep和β值与青年组和中年组的差异显著。此外，老年组内这两个值的偏差也很大。研究发现，随着硬化改变的进展，衰老对腹主动脉弹性特性有影响，且个体差异较大。
