Division of Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Division of Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
Kidney Int. 2022 Mar;101(3):462-464. doi: 10.1016/j.kint.2021.12.023.
Cardiovascular disease is the leading cause of death in children and adults with chronic kidney disease. In this issue, Sugianto et al. demonstrated signs of increased cardiovascular damage (vascular stiffness) in children with chronic kidney disease and highlighted an increased susceptibility of girls, especially in the context of declining kidney function and longer transplant wait times. Understanding the determinants leading to these differences are essential to address the disparity in outcomes in children with chronic kidney disease.
心血管疾病是慢性肾脏病儿童和成人的主要死亡原因。在本期杂志中，Sugianto 等人证明了慢性肾脏病儿童存在心血管损伤（血管僵硬）迹象，并强调了女孩的易感性增加，尤其是在肾功能下降和移植等待时间延长的情况下。了解导致这些差异的决定因素对于解决慢性肾脏病儿童结局差异至关重要。
