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Chronic kidney disease: Definition, updated epidemiology, staging, and mechanisms of increased cardiovascular risk.慢性肾脏病：定义、更新后的流行病学、分期及心血管风险增加的机制
J Clin Hypertens (Greenwich). 2021 Apr;23(4):831-834. doi: 10.1111/jch.14186. Epub 2021 Jan 17.
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Chronic kidney disease measures for cardiovascular risk prediction.慢性肾脏病心血管风险预测的衡量指标。
Atherosclerosis. 2021 Oct;335:110-118. doi: 10.1016/j.atherosclerosis.2021.09.007. Epub 2021 Sep 9.
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Historical Neighborhood Redlining and Cardiovascular Risk in Patients With Chronic Kidney Disease.慢性肾脏病患者的历史社区红线划定与心血管风险
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Getting to the Heart and Soul of Chronic Kidney Disease.探寻慢性肾脏病的核心与本质
J Am Heart Assoc. 2020 Aug 4;9(15):e017427. doi: 10.1161/JAHA.120.017427. Epub 2020 Jul 22.
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Associations Between Kidney Disease Measures and Regional Pulse Wave Velocity in a Large Community-Based Cohort: The Atherosclerosis Risk in Communities (ARIC) Study.在一个大型社区队列中，肾脏疾病指标与区域脉搏波速度的相关性：动脉粥样硬化风险社区（ARIC）研究。
Am J Kidney Dis. 2018 Nov;72(5):682-690. doi: 10.1053/j.ajkd.2018.04.018. Epub 2018 Jul 12.
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A High-Fat Diet Increases Kidney Fibrosis Through Regulating TGF-β and PDGF-β Signaling Pathways in Normotensive and Hypertensive Rat Models.高脂饮食通过调节正常血压和高血压大鼠模型中的TGF-β和PDGF-β信号通路增加肾纤维化。
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Cognitive Impairment in Chronic Kidney Disease Across Different Stages: The Role of Structural and Perfusion-Driven Functional Connectivity Changes.不同阶段慢性肾脏病中的认知障碍：结构和灌注驱动的功能连接变化的作用
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The efficacy of Lacticaseibacillus paracasei MSMC39-1 and Bifidobacterium animalis TA-1 probiotics in modulating gut microbiota and reducing the risk of the characteristics of metabolic syndrome: A randomized, double-blinded, placebo-controlled study.副干酪乳杆菌MSMC39-1和动物双歧杆菌TA-1益生菌在调节肠道微生物群及降低代谢综合征特征风险方面的功效：一项随机、双盲、安慰剂对照研究。
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Built environment and chronic kidney disease: current state and future directions.建筑环境与慢性肾脏病：现状与未来方向
Curr Opin Nephrol Hypertens. 2025 Mar 1;34(2):143-150. doi: 10.1097/MNH.0000000000001048. Epub 2024 Nov 21.
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Kidney injury: the spleno-renal connection and splenic tyrosine kinase.肾损伤：脾肾连接与脾酪氨酸激酶
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Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials.他汀类药物治疗与肾病患者的C反应蛋白：一项随机临床试验的系统评价和荟萃分析
Curr Drug Targets. 2025;26(2):132-145. doi: 10.2174/0113894501302428240909150925.
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A six-year study in a real-world population reveals an increased incidence of dyslipidemia during COVID-19.一项针对真实人群的六年研究显示，在 COVID-19 期间血脂异常的发病率增加。
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本文引用的文献

1
Noninvasive markers of arterial stiffness and renal outcomes in patients with chronic kidney disease.慢性肾脏病患者动脉僵硬度和肾脏结局的无创标志物。
J Clin Hypertens (Greenwich). 2021 Apr;23(4):823-830. doi: 10.1111/jch.14185. Epub 2021 Feb 1.
2
What Is the Utility of KDIGO Criteria to Identify High-Risk Populations?KDIGO标准在识别高危人群方面的效用是什么？
Am J Kidney Dis. 2021 Jan;77(1):7-8. doi: 10.1053/j.ajkd.2020.10.002.
3
Hospitalizations among adults with chronic kidney disease in the United States: A cohort study.美国慢性肾脏病成人患者的住院情况：一项队列研究。
PLoS Med. 2020 Dec 11;17(12):e1003470. doi: 10.1371/journal.pmed.1003470. eCollection 2020 Dec.
4
Circadian Variation and Arterial Stiffness in Chronic Kidney Disease and Their Treatment.慢性肾脏病中的昼夜节律变化与动脉僵硬度及其治疗
Am J Hypertens. 2021 May 22;34(5):456-458. doi: 10.1093/ajh/hpaa197.
5
Diabetes Management in Chronic Kidney Disease: Synopsis of the 2020 KDIGO Clinical Practice Guideline.慢性肾脏病中的糖尿病管理：2020KDIGO 临床实践指南概要。
Ann Intern Med. 2021 Mar;174(3):385-394. doi: 10.7326/M20-5938. Epub 2020 Nov 10.
6
Genetics of adrenergic signaling drives coronary artery calcification.肾上腺素能信号传导的遗传学驱动冠状动脉钙化。
Atherosclerosis. 2020 Oct;310:88-90. doi: 10.1016/j.atherosclerosis.2020.07.025. Epub 2020 Aug 17.
7
Cardiovascular complications of chronic kidney disease: pioneering studies.慢性肾脏病的心血管并发症：开创性研究
Kidney Int. 2020 Sep;98(3):522-526. doi: 10.1016/j.kint.2020.07.001.
8
National Trends in the Prevalence of Chronic Kidney Disease Among Racial/Ethnic and Socioeconomic Status Groups, 1988-2016.1988 年至 2016 年，不同种族/民族和社会经济地位群体中慢性肾脏病的流行趋势。
JAMA Netw Open. 2020 Jul 1;3(7):e207932. doi: 10.1001/jamanetworkopen.2020.7932.
9
Environmental and Occupational Risk Factors Associated with Chronic Kidney Disease of Unknown Etiology in West Javanese Rice Farmers, Indonesia.印度尼西亚西爪哇水稻种植者不明病因慢性肾脏病的环境和职业危险因素。
Int J Environ Res Public Health. 2020 Jun 23;17(12):4521. doi: 10.3390/ijerph17124521.
10
Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference.肾功能与疾病的命名：改善全球肾脏病预后组织（KDIGO）共识会议报告
Kidney Int. 2020 Jun;97(6):1117-1129. doi: 10.1016/j.kint.2020.02.010. Epub 2020 Mar 9.

Chronic kidney disease: Definition, updated epidemiology, staging, and mechanisms of increased cardiovascular risk.

作者信息

Wilson Scott, Mone Pasquale, Jankauskas Stanislovas S, Gambardella Jessica, Santulli Gaetano

机构信息

Department of Medicine, Wilf Family Cardiovascular Research Institute, Einstein Institute for Aging Research, Albert Einstein College of Medicine, New York, NY, USA.

Department of Molecular Pharmacology, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), Fleischer Institute for Diabetes and Metabolism (FIDAM), Albert Einstein College of Medicine, New York, NY, USA.

出版信息

J Clin Hypertens (Greenwich). 2021 Apr;23(4):831-834. doi: 10.1111/jch.14186. Epub 2021 Jan 17.

DOI:10.1111/jch.14186
PMID:33455061
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8035205/
Abstract
摘要