Brandes R, Tsur R, Arad R, Adler J H
Comp Biochem Physiol B. 1986;83(4):837-9. doi: 10.1016/0305-0491(86)90156-2.
The effect of insulin on [3H]oleate binding to delipidated liver cytosolic proteins was studied in four groups of animals: untreated rats, streptozotocin induced diabetic rats, Psammomys obesus fed salt bush diet, and Psammomys obesus fed ordinary laboratory chow. The distribution of the protein bound [3H]oleate between low and high molecular weight cytosolic proteins in Psammomys differed from the distribution found in rats. Diet induced high insulin diabetes in Psammomys and streptozotocin induced low insulin diabetes in rats, modulated [3H]oleate binding in the same manner.
在四组动物中研究了胰岛素对[3H]油酸与脱脂肝脏胞质蛋白结合的影响:未处理的大鼠、链脲佐菌素诱导的糖尿病大鼠、喂食盐灌木饮食的肥胖沙鼠以及喂食普通实验室饲料的肥胖沙鼠。肥胖沙鼠中与[3H]油酸结合的蛋白质在低分子量和高分子量胞质蛋白之间的分布与大鼠中的分布不同。饮食诱导肥胖沙鼠出现高胰岛素性糖尿病,链脲佐菌素诱导大鼠出现低胰岛素性糖尿病,二者以相同方式调节[3H]油酸的结合。