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秋水仙碱在白塞病中的应用。

Use of colchicine in Behçet's syndrome.

作者信息

Sander H M, Randle H W

出版信息

Cutis. 1986 May;37(5):344-8.

PMID:3519102
Abstract

Colchicine is of benefit in the treatment of ocular, articular, oral, and genital lesions in BS. Polymorphonuclear neutrophil function, which is important in the pathogenesis of the disease, is modified by the drug. There is no evidence that colchicine alters the tendency for this disease to become chronic; however, the drug lessens the severity of certain manifestations and does not have the more deleterious side effects of prolonged steroid and immunosuppressive regimens.

摘要

秋水仙碱对治疗贝赫切特综合征的眼部、关节、口腔和生殖器病变有益。该药物可改变在疾病发病机制中起重要作用的多形核中性粒细胞功能。没有证据表明秋水仙碱会改变这种疾病转为慢性的倾向;然而,该药物可减轻某些症状的严重程度,且没有长期使用类固醇和免疫抑制疗法带来的更有害的副作用。

相似文献

1
Use of colchicine in Behçet's syndrome.秋水仙碱在白塞病中的应用。
Cutis. 1986 May;37(5):344-8.
2
[Behçet's disease. Apropos of 32 cases].[白塞病。关于32例病例]
Rev Rhum Mal Osteoartic. 1986 Nov;53(11):621-4.
3
Colchicine in the treatment of the cutaneous manifestations of Behçet's disease.秋水仙碱治疗白塞病的皮肤表现
Br J Dermatol. 1981 Jan;104(1):67-9. doi: 10.1111/j.1365-2133.1981.tb01713.x.
4
[Treatment of Behçet's syndrome with colchicine].[秋水仙碱治疗白塞病]
Riv Eur Sci Med Farmacol. 1989 Jun;11(3):257-61.
5
Infliximab monotherapy versus infliximab and colchicine combination therapy in patients with Behçet's disease.英夫利昔单抗单药治疗与英夫利昔单抗和秋水仙碱联合治疗 Behçet 病患者的效果比较。
Ocul Immunol Inflamm. 2012 Jun;20(3):193-7. doi: 10.3109/09273948.2012.665124. Epub 2012 Apr 9.
6
[Behcet's disease. Trial treatment with colchicine].[白塞病。秋水仙碱试验性治疗]
Ann Dermatol Venereol. 1982;109(6-7):593-4.
7
[Use of colchicine in the treatment of Behçet's disease].[秋水仙碱在白塞病治疗中的应用]
G Ital Dermatol Venereol. 1985 Mar-Apr;120(2):159-63.
8
Plasma thrombomodulin levels in patients with Behçet's disease.
Rheumatol Int. 2003 May;23(3):130-3. doi: 10.1007/s00296-002-0258-z. Epub 2003 Feb 21.
9
Management of necrotizing vasculitis with colchicine. Improvement in patients with cutaneous lesions and Behcet's syndrome.秋水仙碱治疗坏死性血管炎。皮肤病变患者和白塞病患者病情改善。
Arch Dermatol. 1979 Nov;115(11):1303-6.
10
Investigation of ABCB1 gene polymorphism with colchicine response in Behçet's disease.白塞病中ABCB1基因多态性与秋水仙碱反应的研究。
Genet Mol Res. 2011 Jan 4;10(1):1-6. doi: 10.4238/vol10-1gmr824.

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Overlapping Science in Radiation and Sulfur Mustard Exposures of Skin and Lung: Consideration of Models, Mechanisms, Organ Systems, and Medical Countermeasures: Overlapping science in radiation and sulfur mustard injuries to lung and skin.辐射和硫芥暴露于皮肤和肺部的重叠科学:考虑模型、机制、器官系统和医疗对策:辐射和硫芥对肺和皮肤损伤的重叠科学。
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Colchicine in Managing Skin Conditions: A Systematic Review.秋水仙碱治疗皮肤疾病:一项系统评价
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The effect of colchicine treatment on spermatozoa: a cytogenetic approach.
秋水仙碱治疗对精子的影响:一种细胞遗传学方法。
J Assist Reprod Genet. 1999 Oct;16(9):504-7. doi: 10.1023/a:1020511318806.
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Colchicine--expanding horizons.秋水仙碱——拓展视野。
Postgrad Med J. 1991 Mar;67(785):223-6. doi: 10.1136/pgmj.67.785.223.