Westaby D, Williams R
Endoscopy. 1986 May;18 Suppl 2:28-31. doi: 10.1055/s-2007-1018423.
Elective sclerotherapy, to obliterate oesophageal varices, is discussed with particular reference to the results of three controlled trials. There is strong support from each of these studies for the prevention of rebleeding. However, the results for overall survival are conflicting. This discrepancy is discussed in relationship to major differences in trial design. Different techniques of injection sclerotherapy are reviewed, although there is a paucity of comparative data. A prospective study is reported in which 147 patients were followed after initial obliteration of varices, in order to document the rate of recurrence of varices, the associated rate of rebleeding and hence the need for, and timing of, follow-up endoscopy.
本文特别参考三项对照试验的结果，讨论了用于消除食管静脉曲张的选择性硬化疗法。这些研究均有力支持预防再出血。然而，总体生存率的结果存在矛盾。针对试验设计中的主要差异，对这种差异进行了讨论。尽管缺乏比较数据，但仍对注射硬化疗法的不同技术进行了综述。报告了一项前瞻性研究，对147例静脉曲张初次消除后的患者进行随访，以记录静脉曲张的复发率、相关的再出血率，从而确定随访内镜检查的必要性和时机。
