Szczepanik A B, Rudowski W J
Department of Surgery, Research Institute of Hematology, Warsaw, Poland.
Ann R Coll Surg Engl. 1988 Jan;70(1):24-8.
Endoscopic injection sclerotherapy of oesophageal varices was performed in 71 patients: 50 with intrahepatic and 21 with extrahepatic block. In summary 330 procedures were done: 220 under general anaesthesia using the Negus rigid oesophagoscope and 110 with diazepam as premedication using a flexible, fibreoptic endoscope. Definitive control of variceal haemorrhage was achieved in 30 of 34 emergency admissions (88%). The hospital mortality in acute variceal bleeding was 26.5%. Elective, repeated sclerotherapy was performed in 60 patients. In 43 patients complete obliteration of varices or their marked reduction were observed. Rebleeding occurred in 23% and major complications in 17% of patients. The overall one year survival rate was 82%. We consider sclerotherapy as a method of choice in bleeding oesophageal varices uncontrollable by vasopressin and balloon tamponade. It also represents a valuable method of preventing rebleeding particularly in patients with a high operative risk.
对71例患者实施了内镜下食管静脉曲张硬化治疗:50例为肝内阻塞,21例为肝外阻塞。总共进行了330次操作:220次在全身麻醉下使用Negus硬食管镜,110次以地西泮作为术前用药,使用纤维光学软式内镜。34例急诊入院患者中有30例(88%)实现了曲张静脉出血的最终控制。急性曲张静脉出血的医院死亡率为26.5%。60例患者接受了择期重复硬化治疗。43例患者观察到静脉曲张完全消失或明显缩小。23%的患者再次出血,17%的患者出现严重并发症。总体一年生存率为82%。我们认为硬化治疗是一种对血管加压素和气囊压迫无法控制的食管静脉曲张出血的首选方法。它也是预防再次出血的一种有价值的方法,特别是对于手术风险高的患者。