Suppr超能文献

创伤性脑损伤患者中连枷和非连枷肋骨骨折模式的手术固定与非手术治疗。

Surgical stabilization versus nonoperative treatment for flail and non-flail rib fracture patterns in patients with traumatic brain injury.

机构信息

Trauma Research Unit Department of Surgery, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Department of Surgery, HonorHealth John C. Lincoln Medical Center, Phoenix, AZ, 85020, USA.

出版信息

Eur J Trauma Emerg Surg. 2022 Aug;48(4):3327-3338. doi: 10.1007/s00068-022-01906-1. Epub 2022 Feb 22.

Abstract

PURPOSE

Literature on outcomes after SSRF, stratified for rib fracture pattern is scarce in patients with moderate to severe traumatic brain injury (TBI; Glasgow Coma Scale ≤ 12). We hypothesized that SSRF is associated with improved outcomes as compared to nonoperative management without hampering neurological recovery in these patients.

METHODS

A post hoc subgroup analysis of the multicenter, retrospective CWIS-TBI study was performed in patients with TBI and stratified by having sustained a non-flail fracture pattern or flail chest between January 1, 2012 and July 31, 2019. The primary outcome was mechanical ventilation-free days and secondary outcomes were in-hospital outcomes. In multivariable analysis, outcomes were assessed, stratified for rib fracture pattern.

RESULTS

In total, 449 patients were analyzed. In patients with a non-flail fracture pattern, 25 of 228 (11.0%) underwent SSRF and in patients with a flail chest, 86 of 221 (38.9%). In multivariable analysis, ventilator-free days were similar in both treatment groups. For patients with a non-flail fracture pattern, the odds of pneumonia were significantly lower after SSRF (odds ratio 0.29; 95% CI 0.11-0.77; p = 0.013). In patients with a flail chest, the ICU LOS was significantly shorter in the SSRF group (beta, - 2.96 days; 95% CI - 5.70 to - 0.23; p = 0.034).

CONCLUSION

In patients with TBI and a non-flail fracture pattern, SSRF was associated with a reduced pneumonia risk. In patients with TBI and a flail chest, a shorter ICU LOS was observed in the SSRF group. In both groups, SSRF was safe and did not hamper neurological recovery.

摘要

目的

在格拉斯哥昏迷评分(GCS)≤12 的中重度创伤性脑损伤(TBI)患者中,关于创伤性连枷胸固定术(SSRFI)后结局的文献,按肋骨骨折模式分层的研究较少。我们假设与非手术治疗相比,SSRFI 可改善患者的结局,同时不会影响神经恢复。

方法

对多中心回顾性 CWIS-TBI 研究进行了一项事后亚组分析,该研究纳入了 2012 年 1 月 1 日至 2019 年 7 月 31 日期间发生 TBI 且存在非连枷性或连枷胸的患者。主要结局是无机械通气天数,次要结局是院内结局。在多变量分析中,根据肋骨骨折模式进行分层,评估了结局。

结果

共分析了 449 例患者。在非连枷性骨折模式患者中,228 例中有 25 例(11.0%)接受了 SSRFI,而在连枷胸患者中,221 例中有 86 例(38.9%)。在多变量分析中,两组患者的无通气天数相似。对于非连枷性骨折模式患者,SSRFI 后肺炎的几率明显降低(比值比 0.29;95%CI 0.11-0.77;p=0.013)。在连枷胸患者中,SSRFI 组 ICU 住院时间明显缩短(β,-2.96 天;95%CI -5.70 至 -0.23;p=0.034)。

结论

在 TBI 且非连枷性骨折模式患者中,SSRFI 与降低肺炎风险相关。在 TBI 且连枷胸患者中,SSRFI 组 ICU 住院时间较短。在两组患者中,SSRFI 是安全的,且不会影响神经恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae46/9360098/d9dfd0ddef21/68_2022_1906_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验