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治疗方式是否会影响肋骨和锁骨联合损伤患者的医院获得性肺炎及其他院内结局?一项回顾性队列的倾向评分加权分析。

Does the treatment modality affect nosocomial pneumonia and other in-hospital outcomes in patients with combined injuries to the ribs and clavicle? A propensity score weighted analysis of a retrospective cohort.

作者信息

Kobes Tim, van Baal Mark C P M, Heng Marilyn

机构信息

Department of Orthopedic Surgery, Harvard Medical School Orthopedic Trauma Initiative, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02115, USA.

Department of Trauma Surgery, University Medical Center Utrecht, PO Box 85500, Utrecht, GA, 3508, The Netherlands.

出版信息

Arch Orthop Trauma Surg. 2024 Dec 21;145(1):81. doi: 10.1007/s00402-024-05661-3.

Abstract

OBJECTIVE

What is the effect of surgical or conservative treatment on the in-hospital outcomes of patients with combined fractures of the clavicle and ribs?

DESIGN

Retrospective cohort study.

SETTING

Two level-1 trauma centers and academic teaching hospitals in Boston, Massachusetts.

PATIENTS

All adult patients with a clavicle fracture and ≥3 rib fractures admitted from 2016 to 2021.

INTERVENTION

None.

MAIN OUTCOME MEASUREMENTS

Nosocomial pneumonia, hospital length-of-stay (HLOS), ICU length-of-stay (ILOS), days on mechanical ventilation (DMV).

RESULTS

252 patients were included (212 conservative, 40 surgical; median age 62 years, 67% male). The median ISS and GCS scores were 17 and 15, respectively. Thirty-seven patients developed nosocomial pneumonia. For clavicle fixation (n = 26), the OR for pneumonia was 0.3 (95% CI 0.0-2.2), ILOS had a ß-coefficient of -2.6 (95% CI -5.9-0.8), and DMV a ß-coefficient of -3.6 (95% CI -12.0-4.8). For rib plating (n = 10), the OR for pneumonia was 1.4 (95% CI 0.2-8.6), HLOS had a ß-coefficient of 4.9 (95% CI -1.6-11.5), and ILOS a ß-coefficient of 4.1 (95% CI -0.4-8.6). For both surgeries (n = 4), the CIs were wide.

CONCLUSION

Clavicle fixation in patients with combined injuries of the clavicle and ribs did not improve nor worsen in-hospital outcomes; the orthopedic surgeon should make a patient-tailored treatment decision. Rib plating did not improve in-hospital outcomes in non-flail patients with a concomitant clavicle fracture. Guidelines on non-flail rib plating could profit from these findings in combination with previous and additional research.

LEVEL OF EVIDENCE

Level III, Therapeutic Study.

摘要

目的

手术治疗或保守治疗对锁骨和肋骨联合骨折患者的院内结局有何影响?

设计

回顾性队列研究。

地点

马萨诸塞州波士顿的两家一级创伤中心和学术教学医院。

患者

2016年至2021年收治的所有成年锁骨骨折且肋骨骨折≥3处的患者。

干预措施

无。

主要观察指标

医院获得性肺炎、住院时间(HLOS)、重症监护病房住院时间(ILOS)、机械通气天数(DMV)。

结果

纳入252例患者(212例保守治疗,40例手术治疗;中位年龄62岁,67%为男性)。中位损伤严重程度评分(ISS)和格拉斯哥昏迷评分(GCS)分别为17分和15分。37例患者发生医院获得性肺炎。对于锁骨固定(n = 26),肺炎的比值比(OR)为0.3(95%置信区间[CI] 0.0 - 2.2),ILOS的β系数为 -2.6(95% CI -5.9 - 0.8),DMV的β系数为 -3.6(95% CI -12.0 - 4.8)。对于肋骨接骨板固定(n = 10),肺炎的OR为1.4(95% CI 0.2 - 8.6),HLOS的β系数为4.9(95% CI -1.6 - 11.5),ILOS的β系数为4.1(95% CI -0.4 - 8.6)。对于两种手术(n = 4),置信区间较宽。

结论

锁骨和肋骨联合损伤患者的锁骨固定未改善也未恶化院内结局;骨科医生应做出针对患者的治疗决策。肋骨接骨板固定对合并锁骨骨折的非连枷胸患者未改善院内结局。非连枷胸肋骨接骨板固定的指南可结合这些发现以及之前和更多的研究而受益。

证据级别

三级,治疗性研究。

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