Kalmar Christopher L, Lang Shih-Shan, Heuer Gregory G, Schreiber Jane E, Tucker Alexander M, Swanson Jordan W, Beslow Lauren A
Division of Plastic and Reconstructive Surgery, Children's Hospital of Philadelphia, PA, Philadelphia, USA.
Division of Neurosurgery, Children's Hospital of Philadelphia, PA, Philadelphia, USA.
Childs Nerv Syst. 2022 May;38(5):893-901. doi: 10.1007/s00381-022-05448-0. Epub 2022 Feb 22.
While the focus of craniosynostosis surgery is to improve head shape, neurocognitive sequelae are common and are incompletely understood. Neurodevelopmental problems that children with craniosynostosis face include cognitive and language impairments, motor delays or deficits, learning disabilities, executive dysfunction, and behavioral problems. Studies have shown that children with multiple suture craniosynostosis have more impairment than children with single-suture craniosynostosis. Children with isolated single-suture subtypes of craniosynostosis such as sagittal, metopic, and unicoronal craniosynostosis can have distinct neurocognitive profiles. In this review, we discuss the unique neurodevelopmental profiles of children with single-suture subtypes of craniosynostosis.
虽然颅缝早闭手术的重点是改善头部形状，但神经认知后遗症很常见且尚未完全了解。患有颅缝早闭的儿童面临的神经发育问题包括认知和语言障碍、运动迟缓或缺陷、学习障碍、执行功能障碍和行为问题。研究表明，多条缝颅缝早闭的儿童比单条缝颅缝早闭的儿童有更多的损伤。患有孤立的单条缝颅缝早闭亚型（如矢状缝、额缝和单冠状缝颅缝早闭）的儿童可能有不同的神经认知特征。在这篇综述中，我们讨论了单条缝颅缝早闭亚型儿童独特的神经发育特征。
