Hua Rongkai, Hua Qingquan
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Mar;36(3):239-242. doi: 10.13201/j.issn.2096-7993.2022.03.017.
Sensorineural hearing loss has long been one of the common diseases in the field of otology. With the increasing research on stem cell therapy, the experiments and applications of stem cell inner ear transplantation are developing rapidly, with some remarkable results and some questions to be considered. The source of stem cells and the transplantation route are crucial, and the immune rejection in the post-transplantation period should not be ignored. This paper will review the issues related to stem cell source, transplantation route and immune rejection in inner ear transplantation, hoping to provide new ideas for research in the field of stem cell inner ear transplantation.
感音神经性听力损失长期以来一直是耳科学领域的常见疾病之一。随着对干细胞治疗研究的不断增加,干细胞内耳移植的实验和应用发展迅速,取得了一些显著成果,但也存在一些问题需要考虑。干细胞的来源和移植途径至关重要,移植后时期的免疫排斥也不容忽视。本文将综述内耳移植中与干细胞来源、移植途径和免疫排斥相关的问题,希望为干细胞内耳移植领域的研究提供新思路。