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计算机断层导航辅助初次全膝关节置换术治疗股骨远端巨细胞瘤磷酸钙骨水泥填充术后继发膝关节骨关节炎:1 例报告。

Primary total knee arthroplasty assisted by computed tomography-free navigation for secondary knee osteoarthritis following massive calcium phosphate cement packing for distal femoral giant-cell bone tumor treatment: a case report.

机构信息

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa-shi, Ishikawa-ken, 920-8641, Japan.

出版信息

BMC Musculoskelet Disord. 2022 Feb 22;23(1):170. doi: 10.1186/s12891-022-05131-0.

Abstract

BACKGROUND

Giant cell tumor of bone (GCTB) is an intermediate tumor commonly arising from the epiphysis of the distal femur and proximal tibia. Standard GCTB treatment is joint-preserving surgery performed using thorough curettage and the filling of the cavity with allo-, auto-, polymethyl methacrylate (PMMA), or synthetic bone graft. Calcium phosphate cement (CPC) is an artificial bone substitute, which has the benefit of being able to adjust defects, consequently inducing immediate mechanical strength, and promoting biological healing. Secondary osteoarthritis may occur following GCTB treatment and may need additional surgery if severe. However, details regarding surgery for secondary osteoarthritis have not been fully elucidated. There are no reports on the use of total knee arthroplasty (TKA) for the treatment of secondary osteoarthritis following CPC packing. The insertion of an alignment rod is a standard procedure in TKA; however, it was difficult to perform in this case due to CPC. Therefore, we used a computed tomography (CT)-free navigation system to assist the distal femur cut. This study presents a knee joint secondary osteoarthritis case following CPC packing for GCTB curettage that was treated with standard TKA.

CASE PRESENTATION

A 67-year-old Japanese woman, who was previously diagnosed with left distal femur GCTB and was treated by curettage and CPC packing 7 years ago, complained of severe knee pain. Left knee joint plain radiography revealed Kellgren and Lawrence (K-L) grade 4 osteoarthritis without evidence of tumor recurrence. Therefore, she was scheduled for TKA. There are no reports on the cutting of a femoral condyle surface with massive CPC with accurate alignment. Because it is difficult to insert the alignment rod intramedullary and cut the femoral condyle with CPC, we planned CT-free navigation-guided surgery for accurate bone cutting using an oscillating tip saw system to prevent CPC cracks. We performed standard TKA without complications, as planned. Postoperative X-ray showed normal alignment. Knee Society Knee Score (KSKS) and Knee Society Function Score (KSFS) ameliorated from 27 and 29 to 64 and 68, respectively The patient can walk without a cane postoperatively.

CONCLUSION

There was no report about the surface TKA guided by CT-free navigation after primary GCT surgery with CPC. We believe that this case report will help in planning salvage surgery for secondary osteoarthritis after CPC packing.

摘要

背景

骨巨细胞瘤(GCTB)是一种中间性肿瘤,通常发生在远端股骨和近端胫骨的骨骺。GCTB 的标准治疗方法是采用彻底刮除,并使用同种异体、自体、聚甲基丙烯酸甲酯(PMMA)或合成骨移植物填充空腔。磷酸钙骨水泥(CPC)是一种人造骨替代品,其优点是能够调整缺损,从而立即产生机械强度,并促进生物愈合。GCTB 治疗后可能会发生继发性骨关节炎,如果严重的话可能需要再次手术。然而,关于 CPC 填充后继发性骨关节炎手术的细节尚未完全阐明。没有关于使用全膝关节置换术(TKA)治疗 CPC 填充后继发性骨关节炎的报告。在 TKA 中,插入定位杆是一项标准程序;然而,由于 CPC 的存在,这在本例中很难进行。因此,我们使用计算机断层扫描(CT)免费导航系统来辅助股骨远端的切割。本研究介绍了一例 GCTB 刮除术后用 CPC 填充治疗后膝关节继发性骨关节炎的病例,该患者接受了标准的 TKA 治疗。

病例介绍

一位 67 岁的日本女性,7 年前曾被诊断为左侧股骨远端 GCTB,并接受了刮除术和 CPC 填充治疗,她主诉膝关节严重疼痛。左膝关节 X 线平片显示 Kellgren 和 Lawrence(K-L)分级 4 级骨关节炎,无肿瘤复发迹象。因此,她被安排进行 TKA。目前尚无关于使用大量 CPC 进行股骨髁表面切割并进行准确对齐的报道。由于难以将定位杆插入髓内并使用 CPC 切割股骨髁,我们计划使用摆动锯系统进行 CT 免费导航引导下的手术,以进行准确的骨切割,防止 CPC 出现裂缝。我们按照计划进行了标准的 TKA,没有出现并发症。术后 X 线显示正常对齐。膝关节协会膝关节评分(KSKS)和膝关节协会功能评分(KSFS)分别从 27 和 29 改善至 64 和 68,患者术后可无需拐杖行走。

结论

目前尚无关于原发性 GCT 手术后使用 CPC 引导 CT 免费导航进行表面 TKA 的报道。我们相信,本病例报告将有助于规划 CPC 填充后继发性骨关节炎的挽救性手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25b/8864852/0b2375af779f/12891_2022_5131_Fig1_HTML.jpg

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