不使用全氟碳液体治疗复杂性视网膜脱离的玻璃体切除术：一项真实世界数据及回顾性研究

Vitrectomy for Complicated Retinal Detachment Without the Use of Perfluorocarbon Liquid: A Real-World Data and Retrospective Study.

作者信息

Bai Ye, Song Qi, Liu Jing, Wu Qin-Xing, Qin Xue-Jiao

机构信息

Eye Centre of Shandong University, The Second Hospital of Shandong University, No. 247 Beiyuan Street, Jinan, 250012, Shandong, People's Republic of China.

Department of Ophthalmology, Xi'an People's Hospital, Xi'an, People's Republic of China.

出版信息

Ophthalmol Ther. 2022 Apr;11(2):857-868. doi: 10.1007/s40123-022-00479-x. Epub 2022 Feb 23.

DOI:10.1007/s40123-022-00479-x

PMID:35195877

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8927548/

Abstract

INTRODUCTION

This study aimed to evaluate the effectiveness of vitrectomy without using perfluorocarbon liquid (PFCL) for the treatment of complicated retinal detachment (RD).

METHODS

The utilisation of PFCL was calculated in four hospitals in 2020 and in one hospital every year from 2012 to 2020. A case series of 320 RD eyes treated with vitrectomy without the use of perfluorocarbon liquid (VWTPL) was followed up for 1-26 months. The rate of retinal reattachment (RR) and postoperative visual acuity (VA, LogMAR) was evaluated. Furthermore, factors influencing RR and VA were analysed.

RESULTS

The overall utilisation of PFCL was 43.87% (42.74%, 45.83%, 62.39% and 4.5%). The annual utilisation was 46.94%, 20.43%, 46.73%, 47.41%, 20%, 17.24%, 7.60%, 10.67% and 4.49% from 2012 to 2020. The VA of 320 eyes improved from 1.96 ± 1.07 preoperatively to 1.43 ± 0.92 (LogMAR, p < 0.001) 1 week post-operation. In the follow-up of 1-26 months (median: 9 months), the primary and final RR was 87.37% and 95.56%, respectively. Age, uveitis, recurrent RD, the number of detached retinal quadrants, aPVR and preoperative VA were considered as the factors influencing postoperative VA. Moreover, preoperative VA and preoperative intraocular pressure were the factors influencing RR.

CONCLUSION

The utilisation of PFCL varies amongst hospitals with a highest percentage of 62.39%. VWTPL is safe and effective, thereby saving costs and preventing complications related to PFCL.

TRIAL REGISTRATION

ChiCTR-ORC-17014225.

摘要

引言

本研究旨在评估不使用全氟碳液（PFCL）的玻璃体切除术治疗复杂性视网膜脱离（RD）的有效性。

方法

计算了2020年四家医院以及2012年至2020年每年一家医院的PFCL使用情况。对320例接受不使用全氟碳液的玻璃体切除术（VWTPL）治疗的RD患眼进行了1至26个月的随访。评估了视网膜复位率（RR）和术后视力（VA，LogMAR）。此外，分析了影响RR和VA的因素。

结果

PFCL的总体使用率为43.87%（42.74%、45.83%、62.39%和4.5%）。2012年至2020年的年使用率分别为46.94%、20.43%、46.73%、47.41%、20%、17.24%、7.60%、10.67%和4.49%。320只眼的视力在术后1周从术前平均1.96±1.07（LogMAR）提高到1.4３±0.92（p＜0.001）。在1至26个月（中位数：9个月）的随访中，初次和最终RR分别为87.37%和95.56%。年龄、葡萄膜炎、复发性RD、视网膜脱离象限数、增殖性玻璃体视网膜病变（PVR）和术前视力被视为影响术后视力的因素。此外，术前视力和术前眼压是影响RR的因素。