Sheng Yan, Sun Wen, Mo Bin, Yu Ya-Jie, Gu Yang-Shun, Liu Wu
Department of Ophthalmology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China ; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing 100730, China.
Int J Ophthalmol. 2012;5(5):591-5. doi: 10.3980/j.issn.2222-3959.2012.05.09. Epub 2012 Oct 18.
To investigate the efficacy of non-buckled vitrectomy with classical endotamponade agents in the treatment of primary retinal detachment (RD) complicated by inferior breaks and proliferative vitreoretinophathy (PVR).
A retrospective, consecutive and case series study of 40 patients with inferior break RD and PVR ≥C1 was conducted. All patients underwent a standard 3-port 20-gauge pars plana vitrectomy (PPV) with gas or silicone oil tamponade without supplementary scleral buckling. The vitreous and all proliferative membrane were completely removed, and retinectomy was performed when necessary. The mean follow-up was 12.5 months. The primary and final anatomic success rate, visual acuity and complications were recorded and analyzed.
Primary anatomic success rate was achieved in 35 of 40 eyes (87.5%) and the final anatomic success rate was 100%. The most common cause of redetachment was recurrent PVR. The best-corrected visual acuity (BCVA) at final follow-up was improved in 34 eyes (85%), remained stable in 1 eye (2.5%), and worsened in 5 eyes (12.5%). The mean visual acuity at final follow-up was improved significantly (P=0.000).
This retrospective study provides evidence that vitrectomy without scleral buckling seemed to be an effective treatment for inferior break RD with PVR. With complete removal of vitreous and proliferative membranes and timing of retinectomy, the inferior breaks which complicated with PVR could be closed successfully without additional scleral buckling.
探讨非环扎玻璃体切除术联合经典眼内填充剂治疗原发性视网膜脱离(RD)合并下方裂孔及增生性玻璃体视网膜病变(PVR)的疗效。
对40例下方裂孔性RD且PVR≥C1的患者进行回顾性、连续性病例系列研究。所有患者均接受标准的三通道20G经睫状体平坦部玻璃体切除术(PPV),采用气体或硅油填充,不附加巩膜环扎。完全清除玻璃体及所有增殖膜,必要时行视网膜切除术。平均随访12.5个月。记录并分析初次及最终的解剖成功率、视力及并发症情况。
40只眼中35只(87.5%)获得初次解剖成功,最终解剖成功率为100%。视网膜再次脱离最常见的原因是PVR复发。末次随访时,34只眼(85%)最佳矫正视力(BCVA)提高,1只眼(2.5%)视力稳定,5只眼(12.5%)视力下降。末次随访时平均视力显著提高(P = 0.000)。
这项回顾性研究表明,不进行巩膜环扎的玻璃体切除术似乎是治疗合并PVR的下方裂孔性RD的有效方法。通过完全清除玻璃体和增殖膜并适时行视网膜切除术,合并PVR的下方裂孔无需额外巩膜环扎即可成功封闭。