Roenigk R K, Dahl M V
J Am Acad Dermatol. 1986 May;14(5 Pt 2):944-7. doi: 10.1016/s0190-9622(86)70117-5.
Bullous pemphigoid is a chronic blistering disorder characterized by specific clinical, histologic, and immunofluorescent findings. Several variants have been described, including pemphigoid nodularis, which may mimic or evolve from or into prurigo nodularis. The casual relationship between prurigo nodularis and bullous pemphigoid is unknown. We describe a patient with prurigo nodularis and no immunologic evidence of pemphigoid who subsequently developed bullae. Direct immunofluorescence then confirmed the diagnosis of bullous pemphigoid. Apparently this patient had prurigo nodularis and then developed bullous pemphigoid.
大疱性类天疱疮是一种慢性水疱性疾病，其特征为特定的临床、组织学和免疫荧光表现。已描述了几种变体，包括结节性类天疱疮，它可能模仿结节性痒疹或从结节性痒疹演变而来或演变为结节性痒疹。结节性痒疹与大疱性类天疱疮之间的因果关系尚不清楚。我们描述了一名患有结节性痒疹且无类天疱疮免疫证据的患者，该患者随后出现了水疱。直接免疫荧光检查随后证实了大疱性类天疱疮的诊断。显然，这名患者先患有结节性痒疹，然后发展为大疱性类天疱疮。
