Lehman Julia S, Kalaaji Amer N, Rogers Roy S, Stone Richard A
Department of Dermatology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
Cutis. 2011 Nov;88(5):224-6.
Several variants of bullous pemphigoid have been reported including pemphigoid nodularis. Patients with pemphigoid nodularis have clinical features of prurigo nodularis in combination with clinical or immunologic characteristics of bullous pemphigoid. We report the case of a 71-year-old woman with pemphigoid nodularis. The diagnosis was suspected clinically and established by positive indirect immunofluorescence (IIF) findings characteristic of pemphigoid. Results of direct immunofluorescence (DIF) testing were negative, which emphasizes the importance of conducting both DIF and IIF when pemphigoid nodularis is suspected.
已经报道了多种大疱性类天疱疮的变体，包括结节性类天疱疮。结节性类天疱疮患者具有结节性痒疹的临床特征，并伴有大疱性类天疱疮的临床或免疫学特征。我们报告了一例71岁结节性类天疱疮女性患者。临床怀疑诊断，并通过类天疱疮特征性的阳性间接免疫荧光（IIF）结果得以确诊。直接免疫荧光（DIF）检测结果为阴性，这强调了在怀疑结节性类天疱疮时同时进行DIF和IIF检测的重要性。
