Drug Ther Bull. 2022 Mar;60(3):39-43. doi: 10.1136/dtb.2021.000063.
Naldemedine tosylate Rizmoic 200 mcg film-coated tablets Shionogi B.V Treatment of opioid-induced constipation in adult patients who have previously been treated with a laxative 200 mcg/day, taken at the same time every day. Naldemedine may be used with or without a laxative. It must be discontinued if treatment with the opioid is discontinued. £41.72 for 28 tablets Prescription only medicine subject to additional monitoring (▼).
甲磺酸那利肽 Rizmoic 200 mcg 薄膜片 Shionogi B.V. 用于治疗曾接受过泻药治疗的成年患者的阿片类药物诱导性便秘 每天 200 mcg，每天同一时间服用。纳洛肽可以与或不与泻药一起使用。如果停止使用阿片类药物，必须停止使用。 28 片售价 41.72 英镑 仅处方药受额外监控（▼）。
